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Reversal of maternal obesity attenuates hypoxia and improves placental development in the preeclamptic-like BPH/5 mouse model

BACKGROUND: Women with obesity have higher risk of adverse pregnancy outcomes, including preeclampsia (PE). Late-gestational hypertension, aberrant fetoplacental development, and fetal growth restriction (FGR), hallmarks of PE, are observed spontaneously in BPH/5 mice. Similar to obese preeclamptic...

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Detalles Bibliográficos
Autores principales: ADAMS, Daniella M., BECKERS, Kalie F., FLANAGAN, Juliet P., GOMES, Viviane C. L., LIU, Chin-Chi, SONES, Jenny L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569287/
https://www.ncbi.nlm.nih.gov/pubmed/37829603
http://dx.doi.org/10.32604/biocell.2023.029644

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