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CD44s-activated tPA/LRP1-NFκB pathway drives lamellipodia outgrowth in luminal-type breast cancer cells

Some cancer cells migration and metastasis are characterized by the outgrowth of lamellipodia protrusions in which the underlying mechanism remains unclear. Evidence has confirmed that lamellipodia formation could be regulated by various adhesion molecules, such as CD44, and we previously reported t...

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Detalles Bibliográficos
Autores principales: Qiu, Yaqi, Wang, Hui, Guo, Qian, Liu, Yiwen, He, Yiqing, Zhang, Guoliang, Yang, Cuixia, Du, Yan, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569302/
https://www.ncbi.nlm.nih.gov/pubmed/37842093
http://dx.doi.org/10.3389/fcell.2023.1224827