Demethylating agents in combination with CD7-targeted CAR-T for the successful treatment of a case with mixed-phenotype acute leukemia relapsed after allogeneic hematopoietic stem cell transplantation: A Case Report

BACKGROUND: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) has cured many patients with malignant hematologic diseases such as mixed phenotype acute leukemia (MPAL), while those relapsing after allo-HSCT still exhibit high mortality, poor prognosis, and no standard treatment modaliti...

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Detalles Bibliográficos
Autores principales: Han, Ying, Yao, Hao, He, Guang-cui, Lai, Si-han, Deng, Yan, Zhang, Shan, He, Ying, Xiong, Yi-song, Chang, Alex H., Su, Yi, Yi, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569455/
https://www.ncbi.nlm.nih.gov/pubmed/37841245
http://dx.doi.org/10.3389/fimmu.2023.1254010

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