Evidence-based severity assessment of the forced swim test in the rat

The forced swim test (FST) is a traditional assay, which has been used for more than 40 years to assess antidepressant effects of novel drug candidates. In recent years, a debate about the test has focused on the assumption that the FST is highly aversive and burdening for the animals because of the...

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Detalles Bibliográficos
Autores principales: Becker, Laura, Mallien, Anne S., Pfeiffer, Natascha, Brandwein, Christiane, Talbot, Steven R., Bleich, André, Palme, Rupert, Potschka, Heidrun, Gass, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569541/
https://www.ncbi.nlm.nih.gov/pubmed/37824495
http://dx.doi.org/10.1371/journal.pone.0292816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569541/
https://www.ncbi.nlm.nih.gov/pubmed/37824495
http://dx.doi.org/10.1371/journal.pone.0292816

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