Cargando…
Effects of ferulic acid on growth performance and intestinal oxidation indexes of Jilin white geese under lipopolysaccharide-induced oxidative stress
In geese breeding, due to the frequent influence of drugs and environmental and other factors, geese are extremely prone to oxidative stress, which adversely affects growth and development, geese meat quality, down production, and severely affects the development of the geese industry. Ferulic acid...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569607/ https://www.ncbi.nlm.nih.gov/pubmed/37824519 http://dx.doi.org/10.1371/journal.pone.0291955 |
_version_ | 1785119583062982656 |
---|---|
author | Liu, Yingkun Zhang, Tao Jia, Fangyuan Li, Haojia Sun, Meng Fu, Zengyu Zhou, Haizhu Guo, Wei Gao, Yunhang |
author_facet | Liu, Yingkun Zhang, Tao Jia, Fangyuan Li, Haojia Sun, Meng Fu, Zengyu Zhou, Haizhu Guo, Wei Gao, Yunhang |
author_sort | Liu, Yingkun |
collection | PubMed |
description | In geese breeding, due to the frequent influence of drugs and environmental and other factors, geese are extremely prone to oxidative stress, which adversely affects growth and development, geese meat quality, down production, and severely affects the development of the geese industry. Ferulic acid from plant extracts can be used as a feed additive, which is safe and non-toxic, and it can exert certain therapeutic effects on oxidative stress in geese. This experiment investigated the effect of ferulic acid on the growth performance, organs indices, and intestinal oxidative indices of Jilin white geese under lipopolysaccharide-induced oxidative stress. Geese were randomly divided into six groups: C (blank control), L (lipopolysaccharide control), F1 (60 mg/kg ferulic acid), F2 (120 mg/kg ferulic acid), F3 (180 mg/kg ferulic acid), and F4 (240 mg/kg ferulic acid). Groups L and F1–F4 were injected intraperitoneally with 0.5 mg/kg lipopolysaccharide and group C with an equivalent volume of normal saline on days 14,17 and 20, and 10 animals from each group were randomly selected for slaughter on day 21. The results showed that: 1) On day 14, the final body weight and average daily feed intake were significantly higher in group F3 than in group L, and on day 21, the final body weight was significantly higher in group F3 than in group L. 2) The thymus index was significantly higher in group F4 than in group L. 4) In the duodenum, MDA activity was reduced in group C compared with that in group L. 5) In the jejunum and ileum, MDA was significantly lower in group F3 than in group L. These results show that the addition of 180 mg/kg of ferulic acid to the diet can promote the growth of geese and alleviate the damage caused by oxidative stress in all intestinal segments. |
format | Online Article Text |
id | pubmed-10569607 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-105696072023-10-13 Effects of ferulic acid on growth performance and intestinal oxidation indexes of Jilin white geese under lipopolysaccharide-induced oxidative stress Liu, Yingkun Zhang, Tao Jia, Fangyuan Li, Haojia Sun, Meng Fu, Zengyu Zhou, Haizhu Guo, Wei Gao, Yunhang PLoS One Research Article In geese breeding, due to the frequent influence of drugs and environmental and other factors, geese are extremely prone to oxidative stress, which adversely affects growth and development, geese meat quality, down production, and severely affects the development of the geese industry. Ferulic acid from plant extracts can be used as a feed additive, which is safe and non-toxic, and it can exert certain therapeutic effects on oxidative stress in geese. This experiment investigated the effect of ferulic acid on the growth performance, organs indices, and intestinal oxidative indices of Jilin white geese under lipopolysaccharide-induced oxidative stress. Geese were randomly divided into six groups: C (blank control), L (lipopolysaccharide control), F1 (60 mg/kg ferulic acid), F2 (120 mg/kg ferulic acid), F3 (180 mg/kg ferulic acid), and F4 (240 mg/kg ferulic acid). Groups L and F1–F4 were injected intraperitoneally with 0.5 mg/kg lipopolysaccharide and group C with an equivalent volume of normal saline on days 14,17 and 20, and 10 animals from each group were randomly selected for slaughter on day 21. The results showed that: 1) On day 14, the final body weight and average daily feed intake were significantly higher in group F3 than in group L, and on day 21, the final body weight was significantly higher in group F3 than in group L. 2) The thymus index was significantly higher in group F4 than in group L. 4) In the duodenum, MDA activity was reduced in group C compared with that in group L. 5) In the jejunum and ileum, MDA was significantly lower in group F3 than in group L. These results show that the addition of 180 mg/kg of ferulic acid to the diet can promote the growth of geese and alleviate the damage caused by oxidative stress in all intestinal segments. Public Library of Science 2023-10-12 /pmc/articles/PMC10569607/ /pubmed/37824519 http://dx.doi.org/10.1371/journal.pone.0291955 Text en © 2023 Liu et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Liu, Yingkun Zhang, Tao Jia, Fangyuan Li, Haojia Sun, Meng Fu, Zengyu Zhou, Haizhu Guo, Wei Gao, Yunhang Effects of ferulic acid on growth performance and intestinal oxidation indexes of Jilin white geese under lipopolysaccharide-induced oxidative stress |
title | Effects of ferulic acid on growth performance and intestinal oxidation indexes of Jilin white geese under lipopolysaccharide-induced oxidative stress |
title_full | Effects of ferulic acid on growth performance and intestinal oxidation indexes of Jilin white geese under lipopolysaccharide-induced oxidative stress |
title_fullStr | Effects of ferulic acid on growth performance and intestinal oxidation indexes of Jilin white geese under lipopolysaccharide-induced oxidative stress |
title_full_unstemmed | Effects of ferulic acid on growth performance and intestinal oxidation indexes of Jilin white geese under lipopolysaccharide-induced oxidative stress |
title_short | Effects of ferulic acid on growth performance and intestinal oxidation indexes of Jilin white geese under lipopolysaccharide-induced oxidative stress |
title_sort | effects of ferulic acid on growth performance and intestinal oxidation indexes of jilin white geese under lipopolysaccharide-induced oxidative stress |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569607/ https://www.ncbi.nlm.nih.gov/pubmed/37824519 http://dx.doi.org/10.1371/journal.pone.0291955 |
work_keys_str_mv | AT liuyingkun effectsofferulicacidongrowthperformanceandintestinaloxidationindexesofjilinwhitegeeseunderlipopolysaccharideinducedoxidativestress AT zhangtao effectsofferulicacidongrowthperformanceandintestinaloxidationindexesofjilinwhitegeeseunderlipopolysaccharideinducedoxidativestress AT jiafangyuan effectsofferulicacidongrowthperformanceandintestinaloxidationindexesofjilinwhitegeeseunderlipopolysaccharideinducedoxidativestress AT lihaojia effectsofferulicacidongrowthperformanceandintestinaloxidationindexesofjilinwhitegeeseunderlipopolysaccharideinducedoxidativestress AT sunmeng effectsofferulicacidongrowthperformanceandintestinaloxidationindexesofjilinwhitegeeseunderlipopolysaccharideinducedoxidativestress AT fuzengyu effectsofferulicacidongrowthperformanceandintestinaloxidationindexesofjilinwhitegeeseunderlipopolysaccharideinducedoxidativestress AT zhouhaizhu effectsofferulicacidongrowthperformanceandintestinaloxidationindexesofjilinwhitegeeseunderlipopolysaccharideinducedoxidativestress AT guowei effectsofferulicacidongrowthperformanceandintestinaloxidationindexesofjilinwhitegeeseunderlipopolysaccharideinducedoxidativestress AT gaoyunhang effectsofferulicacidongrowthperformanceandintestinaloxidationindexesofjilinwhitegeeseunderlipopolysaccharideinducedoxidativestress |