Proximity-dependent mapping of the HCMV US28 interactome identifies RhoGEF signaling as a requirement for efficient viral reactivation

Human cytomegalovirus (HCMV) encodes multiple putative G protein-coupled receptors (GPCRs). US28 functions as a viral chemokine receptor and is expressed during both latent and lytic phases of virus infection. US28 actively promotes cellular migration, transformation, and plays a major role in media...

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Detalles Bibliográficos
Autores principales: Medica, Samuel, Crawford, Lindsey B., Denton, Michael, Min, Chan-Ki, Jones, Taylor A., Alexander, Timothy, Parkins, Christopher J., Diggins, Nicole L., Streblow, Gabriel J., Mayo, Adam T., Kreklywich, Craig N., Smith, Patricia, Jeng, Sophia, McWeeney, Shannon, Hancock, Meaghan H., Yurochko, Andrew, Cohen, Michael S., Caposio, Patrizia, Streblow, Daniel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569644/
https://www.ncbi.nlm.nih.gov/pubmed/37782657
http://dx.doi.org/10.1371/journal.ppat.1011682

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