Human voltage-gated Na(+) and K(+) channel properties underlie sustained fast AP signaling

Human cortical pyramidal neurons are large, have extensive dendritic trees, and yet have unexpectedly fast input-output properties: Rapid subthreshold synaptic membrane potential changes are reliably encoded in timing of action potentials (APs). Here, we tested whether biophysical properties of volt...

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Detalles Bibliográficos
Autores principales: Wilbers, René, Metodieva, Verjinia D., Duverdin, Sarah, Heyer, Djai B., Galakhova, Anna A., Mertens, Eline J., Versluis, Tamara D., Baayen, Johannes C., Idema, Sander, Noske, David P., Verburg, Niels, Willemse, Ronald B., de Witt Hamer, Philip C., Kole, Maarten H. P., de Kock, Christiaan P. J., Mansvelder, Huibert D., Goriounova, Natalia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569700/
https://www.ncbi.nlm.nih.gov/pubmed/37824607
http://dx.doi.org/10.1126/sciadv.ade3300

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