Lipid kinase PIP5K1A regulates let-7 microRNA biogenesis through interacting with nuclear export protein XPO5

MicroRNAs (miRNAs) are small non-coding RNAs first discovered in Caenorhabditis elegans. The let-7 miRNA is highly conserved in sequence, biogenesis and function from C. elegans to humans. During miRNA biogenesis, XPO5-mediated nuclear export of pre-miRNAs is a rate-limiting step and, therefore, mig...

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Detalles Bibliográficos
Autores principales: Li, Chun, Yoon, Bohyung, Stefani, Giovanni, Slack, Frank J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570020/
https://www.ncbi.nlm.nih.gov/pubmed/37655623
http://dx.doi.org/10.1093/nar/gkad709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570020/
https://www.ncbi.nlm.nih.gov/pubmed/37655623
http://dx.doi.org/10.1093/nar/gkad709

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