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Genome-wide screening reveals metabolic regulation of stop-codon readthrough by cyclic AMP

Translational fidelity is critical for microbial fitness, survival and stress responses. Much remains unknown about the genetic and environmental control of translational fidelity and its single-cell heterogeneity. In this study, we used a high-throughput fluorescence-based assay to screen a knock-o...

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Detalles Bibliográficos
Autores principales:	Lyu, Zhihui, Villanueva, Patricia, O’Malley, Liam, Murphy, Parker, Augenstreich, Jacques, Briken, Volker, Singh, Abhyudai, Ling, Jiqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570021/ https://www.ncbi.nlm.nih.gov/pubmed/37670559 http://dx.doi.org/10.1093/nar/gkad725

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