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Optimisation of TP53 reporters by systematic dissection of synthetic TP53 response elements
TP53 is a transcription factor that controls multiple cellular processes, including cell cycle arrest, DNA repair and apoptosis. The relation between TP53 binding site architecture and transcriptional output is still not fully understood. Here, we systematically examined in three different cell line...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570033/ https://www.ncbi.nlm.nih.gov/pubmed/37650627 http://dx.doi.org/10.1093/nar/gkad718 |