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Recovery of protein synthesis to assay DNA repair activity in transcribed genes in living cells and tissues

Transcription-coupled nucleotide excision repair (TC-NER) is an important DNA repair mechanism that protects against the negative effects of transcription-blocking DNA lesions. Hereditary TC-NER deficiencies cause pleiotropic and often severe neurodegenerative and progeroid symptoms. While multiple...

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Detalles Bibliográficos
Autores principales: van der Woude, Melanie, Davó-Martínez, Carlota, Thijssen, Karen L, Vermeulen, Wim, Lans, Hannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570043/
https://www.ncbi.nlm.nih.gov/pubmed/37522336
http://dx.doi.org/10.1093/nar/gkad642