Cargando…

SFyNCS detects oncogenic fusions involving non-coding sequences in cancer

Fusion genes are well-known cancer drivers. However, most known oncogenic fusions are protein-coding, and very few involve non-coding sequences due to lack of suitable detection tools. We develop SFyNCS to detect fusions of both protein-coding genes and non-coding sequences from transcriptomic seque...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhong, Xiaoming, Luan, Jingyun, Yu, Anqi, Lee-Hassett, Anna, Miao, Yuxuan, Yang, Lixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570049/
https://www.ncbi.nlm.nih.gov/pubmed/37638762
http://dx.doi.org/10.1093/nar/gkad705