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Impaired proteostatic mechanisms other than decreased protein synthesis limit old skeletal muscle recovery after disuse atrophy

BACKGROUND: Skeletal muscle mass and strength diminish during periods of disuse but recover upon return to weight bearing in healthy adults but are incomplete in old muscle. Efforts to improve muscle recovery in older individuals commonly aim at increasing myofibrillar protein synthesis via mammalia...

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Detalles Bibliográficos
Autores principales: Fuqua, Jordan D., Lawrence, Marcus M., Hettinger, Zachary R., Borowik, Agnieszka K., Brecheen, Parker L., Szczygiel, Marcelina M., Abbott, Claire B., Peelor, Frederick F., Confides, Amy L., Kinter, Michael, Bodine, Sue C., Dupont‐Versteegden, Esther E., Miller, Benjamin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570113/
https://www.ncbi.nlm.nih.gov/pubmed/37448295
http://dx.doi.org/10.1002/jcsm.13285