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EQ-5D-5L Value Set for Slovenia

OBJECTIVES: The aim of this valuation study was to produce a value set to support the use of EQ-5D-5L data in decision making in Slovenia. METHODS: The study design followed the published EuroQol research protocol, and a quota sample was defined according to age, sex, and region. Overall, 1012 adult...

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Autores principales: Prevolnik Rupel, Valentina, Ogorevc, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570207/
https://www.ncbi.nlm.nih.gov/pubmed/37341959
http://dx.doi.org/10.1007/s40273-023-01280-9
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author Prevolnik Rupel, Valentina
Ogorevc, Marko
author_facet Prevolnik Rupel, Valentina
Ogorevc, Marko
author_sort Prevolnik Rupel, Valentina
collection PubMed
description OBJECTIVES: The aim of this valuation study was to produce a value set to support the use of EQ-5D-5L data in decision making in Slovenia. METHODS: The study design followed the published EuroQol research protocol, and a quota sample was defined according to age, sex, and region. Overall, 1012 adult respondents completed 10 time trade-off and seven discrete choice experiment tasks in face-to-face interviews. The Tobit model was used to analyse the composite time trade-off (cTTO) data in order to generate values for the 3125 EQ-5D-5L health states. RESULTS: The data showed logical consistency, with more severe states being given lower values. The greatest disutility was shown in the pain/discomfort and anxiety/depression dimensions. In the EQ-5D-5L value set, the values range from −1.09 to 1. With the exception of UA5 (unable to perform usual activities), all other levels on all health dimensions were statistically different from 0 and from each other. Compared with the existing EQ-5D-3L value set, there is a slightly lower share of ‘worse than dead’ states (32.1% compared with 33.7%) and the minimum value is lower. CONCLUSIONS: Results have important implications for users of the EQ-5D-5L in Slovenia and regions. It is a robust and up-to-date value set and should be the preferred value set used in adults in Slovenia and in neighbouring countries without their own value set.
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spelling pubmed-105702072023-10-14 EQ-5D-5L Value Set for Slovenia Prevolnik Rupel, Valentina Ogorevc, Marko Pharmacoeconomics Original Research Article OBJECTIVES: The aim of this valuation study was to produce a value set to support the use of EQ-5D-5L data in decision making in Slovenia. METHODS: The study design followed the published EuroQol research protocol, and a quota sample was defined according to age, sex, and region. Overall, 1012 adult respondents completed 10 time trade-off and seven discrete choice experiment tasks in face-to-face interviews. The Tobit model was used to analyse the composite time trade-off (cTTO) data in order to generate values for the 3125 EQ-5D-5L health states. RESULTS: The data showed logical consistency, with more severe states being given lower values. The greatest disutility was shown in the pain/discomfort and anxiety/depression dimensions. In the EQ-5D-5L value set, the values range from −1.09 to 1. With the exception of UA5 (unable to perform usual activities), all other levels on all health dimensions were statistically different from 0 and from each other. Compared with the existing EQ-5D-3L value set, there is a slightly lower share of ‘worse than dead’ states (32.1% compared with 33.7%) and the minimum value is lower. CONCLUSIONS: Results have important implications for users of the EQ-5D-5L in Slovenia and regions. It is a robust and up-to-date value set and should be the preferred value set used in adults in Slovenia and in neighbouring countries without their own value set. Springer International Publishing 2023-06-21 2023 /pmc/articles/PMC10570207/ /pubmed/37341959 http://dx.doi.org/10.1007/s40273-023-01280-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Original Research Article
Prevolnik Rupel, Valentina
Ogorevc, Marko
EQ-5D-5L Value Set for Slovenia
title EQ-5D-5L Value Set for Slovenia
title_full EQ-5D-5L Value Set for Slovenia
title_fullStr EQ-5D-5L Value Set for Slovenia
title_full_unstemmed EQ-5D-5L Value Set for Slovenia
title_short EQ-5D-5L Value Set for Slovenia
title_sort eq-5d-5l value set for slovenia
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570207/
https://www.ncbi.nlm.nih.gov/pubmed/37341959
http://dx.doi.org/10.1007/s40273-023-01280-9
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