Heme Oxygenase-1-Modified BMMSCs Activate AMPK–Nrf2–FTH1 to Reduce Severe Steatotic Liver Ischemia–Reperfusion Injury

BACKGROUND: Ischemia–reperfusion injury (IRI) is an important cause of graft dysfunction post-liver transplantation, where donor liver with severe steatosis is more sensitive to IRI. Liver IRI involves ferroptosis and can be alleviated by heme oxygenase-1-modified bone marrow mesenchymal stem cells...

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Detalles Bibliográficos
Autores principales: Tian, Xiaorong, Wang, Yuxin, Yuan, Mengshu, Zheng, Weiping, Zuo, Huaiwen, Zhang, Xinru, Song, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570260/
https://www.ncbi.nlm.nih.gov/pubmed/37707747
http://dx.doi.org/10.1007/s10620-023-08102-0

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