KRAS G12V neoantigen specific T cell receptor for adoptive T cell therapy against tumors

KRAS mutations are broadly recognized as promising targets for tumor therapy. T cell receptors (TCRs) can specifically recognize KRAS mutant neoantigens presented by human lymphocyte antigen (HLA) and mediate T cell responses to eliminate tumor cells. In the present study, we identify two TCRs speci...

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Detalles Bibliográficos
Autores principales: Lu, Dan, Chen, Yuan, Jiang, Min, Wang, Jie, Li, Yiting, Ma, Keke, Sun, Wenqiao, Zheng, Xing, Qi, Jianxun, Jin, Wenjing, Chen, Yu, Chai, Yan, Zhang, Catherine W. H., Liang, Hao, Tan, Shuguang, Gao, George F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570350/
https://www.ncbi.nlm.nih.gov/pubmed/37828002
http://dx.doi.org/10.1038/s41467-023-42010-1

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