Maternal diet alters long-term innate immune cell memory in fetal and juvenile hematopoietic stem and progenitor cells in nonhuman primate offspring

Maternal overnutrition increases inflammatory and metabolic disease risk in postnatal offspring. This constitutes a major public health concern due to increasing prevalence of these diseases, yet mechanisms remain unclear. Here, using nonhuman primate models, we show that maternal Western-style diet...

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Detalles Bibliográficos
Autores principales: Nash, Michael J., Dobrinskikh, Evgenia, Soderborg, Taylor K., Janssen, Rachel C., Takahashi, Diana L., Dean, Tyler A., Varlamov, Oleg, Hennebold, Jon D., Gannon, Maureen, Aagaard, Kjersti M., McCurdy, Carrie E., Kievit, Paul, Bergman, Bryan C., Jones, Kenneth L., Pietras, Eric M., Wesolowski, Stephanie R., Friedman, Jacob E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570400/
https://www.ncbi.nlm.nih.gov/pubmed/37058409
http://dx.doi.org/10.1016/j.celrep.2023.112393

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