Purification of linearized template plasmid DNA decreases double-stranded RNA formation during IVT reaction

After the COVID-19 pandemic, messenger RNA (mRNA) has revolutionized traditional vaccine manufacturing. With the increasing number of RNA-based therapeutics, valuable new scientific insights into these molecules have emerged. One fascinating area of study is the formation of double-stranded RNA (dsR...

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Detalles Bibliográficos
Autores principales: Martínez, Juan, Lampaya, Verónica, Larraga, Ana, Magallón, Héctor, Casabona, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570549/
https://www.ncbi.nlm.nih.gov/pubmed/37842641
http://dx.doi.org/10.3389/fmolb.2023.1248511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570549/
https://www.ncbi.nlm.nih.gov/pubmed/37842641
http://dx.doi.org/10.3389/fmolb.2023.1248511

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