Cargando…

Spinopelvic sagittal realignment and incidence of adjacent segment disease after single-segment posterior lumbar inter-body fusion using 12° lordotic cages—a 2-year prospective cohort study

BACKGROUND: The importance of spinopelvic sagittal alignment for adjacent segment disease (ASD) after lumbar fusion surgery has been reported. However, no longitudinal cohort studies have determined the extent to which segmental alignment and spinopelvic global alignment can be achieved using 12° lo...

Descripción completa

Detalles Bibliográficos
Autores principales: Matsumoto, Tomiya, Okuda, Shinya, Nagamoto, Yukitaka, Takahashi, Yoshifumi, Furuya, Masayuki, Iwasaki, Motoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570649/
https://www.ncbi.nlm.nih.gov/pubmed/37841797
http://dx.doi.org/10.21037/jss-23-78
_version_ 1785119815746191360
author Matsumoto, Tomiya
Okuda, Shinya
Nagamoto, Yukitaka
Takahashi, Yoshifumi
Furuya, Masayuki
Iwasaki, Motoki
author_facet Matsumoto, Tomiya
Okuda, Shinya
Nagamoto, Yukitaka
Takahashi, Yoshifumi
Furuya, Masayuki
Iwasaki, Motoki
author_sort Matsumoto, Tomiya
collection PubMed
description BACKGROUND: The importance of spinopelvic sagittal alignment for adjacent segment disease (ASD) after lumbar fusion surgery has been reported. However, no longitudinal cohort studies have determined the extent to which segmental alignment and spinopelvic global alignment can be achieved using 12° lordotic cages in posterior lumbar inter-body fusion (PLIF) and the extent to which the development of ASD can be prevented. The purpose of this study was to analyze changes in segmental and spinopelvic sagittal alignment after single-segment PLIF with 12° lordotic cages, to clarify the relationship between changes in segmental and spinopelvic sagittal alignment, and to report the incidence of ASD at 2 years postoperatively. METHODS: Subjects in this 2-year prospective longitudinal cohort study were 28 patients who had undergone L4/5 PLIF using 12° lordotic cages. Incidence of operative ASD (O-ASD) was evaluated as clinical outcomes. Radiological measurements were examined preoperatively and at 3 months, 1 year and 2 years postoperatively. The following radiographic spinopelvic parameters were measured: segmental lordosis (SL) at L4/5; sagittal vertical axis (SVA); T1 pelvic angle (TPA); thoracic kyphosis (TK); lumbar lordosis (LL); sacral slope (SS); pelvic tilt (PT); and pelvic incidence (PI). With respect to radiological outcomes, changes in SL (ΔSL) and spinopelvic parameters and the incidence of radiological ASD (R-ASD) were evaluated. Correlations of ΔSL and changes in other spinopelvic parameters (ΔSVA, ΔTPA, ΔTK, ΔLL, ΔSS, ΔPT, and ΔPI-LL) between preoperatively and 3 months postoperatively were examined. RESULTS: The follow-up rate was 100% (n=28) at 1 year postoperatively and 96.4% (n=27) at 2 years postoperatively. No cases of O-ASD were seen during 2 years of follow-up. Significant realignment was observed and maintained at 2 years postoperatively in almost all spinopelvic sagittal parameters (SL, SVA, TPA, LL, PT, PI-LL). Regarding the correlation between ΔSL and other parameters, significant correlations were detected with ΔSVA (r=−0.37, P<0.05) and ΔLL (r=0.538, P<0.01). Three cases (11.1%) showed R-ASD at 2 years postoperatively. CONCLUSIONS: PLIF with 12° lordotic cages for L4 degenerative spondylolisthesis improved SL and global sagittal realignment, and achieved satisfactory clinical outcomes with a low incidence of ASD during 2 years of follow-up.
format Online
Article
Text
id pubmed-10570649
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher AME Publishing Company
record_format MEDLINE/PubMed
spelling pubmed-105706492023-10-14 Spinopelvic sagittal realignment and incidence of adjacent segment disease after single-segment posterior lumbar inter-body fusion using 12° lordotic cages—a 2-year prospective cohort study Matsumoto, Tomiya Okuda, Shinya Nagamoto, Yukitaka Takahashi, Yoshifumi Furuya, Masayuki Iwasaki, Motoki J Spine Surg Original Article BACKGROUND: The importance of spinopelvic sagittal alignment for adjacent segment disease (ASD) after lumbar fusion surgery has been reported. However, no longitudinal cohort studies have determined the extent to which segmental alignment and spinopelvic global alignment can be achieved using 12° lordotic cages in posterior lumbar inter-body fusion (PLIF) and the extent to which the development of ASD can be prevented. The purpose of this study was to analyze changes in segmental and spinopelvic sagittal alignment after single-segment PLIF with 12° lordotic cages, to clarify the relationship between changes in segmental and spinopelvic sagittal alignment, and to report the incidence of ASD at 2 years postoperatively. METHODS: Subjects in this 2-year prospective longitudinal cohort study were 28 patients who had undergone L4/5 PLIF using 12° lordotic cages. Incidence of operative ASD (O-ASD) was evaluated as clinical outcomes. Radiological measurements were examined preoperatively and at 3 months, 1 year and 2 years postoperatively. The following radiographic spinopelvic parameters were measured: segmental lordosis (SL) at L4/5; sagittal vertical axis (SVA); T1 pelvic angle (TPA); thoracic kyphosis (TK); lumbar lordosis (LL); sacral slope (SS); pelvic tilt (PT); and pelvic incidence (PI). With respect to radiological outcomes, changes in SL (ΔSL) and spinopelvic parameters and the incidence of radiological ASD (R-ASD) were evaluated. Correlations of ΔSL and changes in other spinopelvic parameters (ΔSVA, ΔTPA, ΔTK, ΔLL, ΔSS, ΔPT, and ΔPI-LL) between preoperatively and 3 months postoperatively were examined. RESULTS: The follow-up rate was 100% (n=28) at 1 year postoperatively and 96.4% (n=27) at 2 years postoperatively. No cases of O-ASD were seen during 2 years of follow-up. Significant realignment was observed and maintained at 2 years postoperatively in almost all spinopelvic sagittal parameters (SL, SVA, TPA, LL, PT, PI-LL). Regarding the correlation between ΔSL and other parameters, significant correlations were detected with ΔSVA (r=−0.37, P<0.05) and ΔLL (r=0.538, P<0.01). Three cases (11.1%) showed R-ASD at 2 years postoperatively. CONCLUSIONS: PLIF with 12° lordotic cages for L4 degenerative spondylolisthesis improved SL and global sagittal realignment, and achieved satisfactory clinical outcomes with a low incidence of ASD during 2 years of follow-up. AME Publishing Company 2023-09-18 2023-09-22 /pmc/articles/PMC10570649/ /pubmed/37841797 http://dx.doi.org/10.21037/jss-23-78 Text en 2023 Journal of Spine Surgery. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Original Article
Matsumoto, Tomiya
Okuda, Shinya
Nagamoto, Yukitaka
Takahashi, Yoshifumi
Furuya, Masayuki
Iwasaki, Motoki
Spinopelvic sagittal realignment and incidence of adjacent segment disease after single-segment posterior lumbar inter-body fusion using 12° lordotic cages—a 2-year prospective cohort study
title Spinopelvic sagittal realignment and incidence of adjacent segment disease after single-segment posterior lumbar inter-body fusion using 12° lordotic cages—a 2-year prospective cohort study
title_full Spinopelvic sagittal realignment and incidence of adjacent segment disease after single-segment posterior lumbar inter-body fusion using 12° lordotic cages—a 2-year prospective cohort study
title_fullStr Spinopelvic sagittal realignment and incidence of adjacent segment disease after single-segment posterior lumbar inter-body fusion using 12° lordotic cages—a 2-year prospective cohort study
title_full_unstemmed Spinopelvic sagittal realignment and incidence of adjacent segment disease after single-segment posterior lumbar inter-body fusion using 12° lordotic cages—a 2-year prospective cohort study
title_short Spinopelvic sagittal realignment and incidence of adjacent segment disease after single-segment posterior lumbar inter-body fusion using 12° lordotic cages—a 2-year prospective cohort study
title_sort spinopelvic sagittal realignment and incidence of adjacent segment disease after single-segment posterior lumbar inter-body fusion using 12° lordotic cages—a 2-year prospective cohort study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570649/
https://www.ncbi.nlm.nih.gov/pubmed/37841797
http://dx.doi.org/10.21037/jss-23-78
work_keys_str_mv AT matsumototomiya spinopelvicsagittalrealignmentandincidenceofadjacentsegmentdiseaseaftersinglesegmentposteriorlumbarinterbodyfusionusing12lordoticcagesa2yearprospectivecohortstudy
AT okudashinya spinopelvicsagittalrealignmentandincidenceofadjacentsegmentdiseaseaftersinglesegmentposteriorlumbarinterbodyfusionusing12lordoticcagesa2yearprospectivecohortstudy
AT nagamotoyukitaka spinopelvicsagittalrealignmentandincidenceofadjacentsegmentdiseaseaftersinglesegmentposteriorlumbarinterbodyfusionusing12lordoticcagesa2yearprospectivecohortstudy
AT takahashiyoshifumi spinopelvicsagittalrealignmentandincidenceofadjacentsegmentdiseaseaftersinglesegmentposteriorlumbarinterbodyfusionusing12lordoticcagesa2yearprospectivecohortstudy
AT furuyamasayuki spinopelvicsagittalrealignmentandincidenceofadjacentsegmentdiseaseaftersinglesegmentposteriorlumbarinterbodyfusionusing12lordoticcagesa2yearprospectivecohortstudy
AT iwasakimotoki spinopelvicsagittalrealignmentandincidenceofadjacentsegmentdiseaseaftersinglesegmentposteriorlumbarinterbodyfusionusing12lordoticcagesa2yearprospectivecohortstudy