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Towards Multiomics-Based Dissection of Anti-EGFR Sensitivity in Colorectal Cancer
Overexpression of the EGFR ligands amphiregulin (AREG)/epiregulin (EREG) may be a surrogate of EGFR dependency regardless of sidedness in metastatic colorectal cancer. High AREG/EREG may be coupled with negative hyper-selection (i.e., lack of genomic drivers of primary resistance beyond RAS and BRAF...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for Cancer Research
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570674/ https://www.ncbi.nlm.nih.gov/pubmed/37594733 http://dx.doi.org/10.1158/1078-0432.CCR-23-1954 |