Integrated Genomic and Transcriptomic Analysis Improves Disease Classification and Risk Stratification of MDS with Ring Sideroblasts

PURPOSE: Ring sideroblasts (RS) define the low-risk myelodysplastic neoplasm (MDS) subgroup with RS but may also reflect erythroid dysplasia in higher risk myeloid neoplasm. The benign behavior of MDS with RS (MDS(RS+)) is limited to SF3B1-mutated cases without additional high-risk genetic events, b...

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Detalles Bibliográficos
Autores principales: Todisco, Gabriele, Creignou, Maria, Bernard, Elsa, Björklund, Ann-Charlotte, Moura, Pedro Luis, Tesi, Bianca, Mortera-Blanco, Teresa, Sander, Birgitta, Jansson, Monika, Walldin, Gunilla, Barbosa, Indira, Reinsbach, Susanne E., Hofman, Isabel Juliana, Nilsson, Christer, Yoshizato, Tetsuichi, Dimitriou, Marios, Chang, David, Olafsdottir, Svannildur, Venckute Larsson, Sigita, Tobiasson, Magnus, Malcovati, Luca, Woll, Petter, Jacobsen, Sten Eirik W., Papaemmanuil, Elli, Hellström-Lindberg, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570683/
https://www.ncbi.nlm.nih.gov/pubmed/37498312
http://dx.doi.org/10.1158/1078-0432.CCR-23-0538

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