Cargando…

Secondary somatic glioblastoma arising from a mature ovarian cystic teratoma in a patient with underlying Li-Fraumeni syndrome

• First report of a secondary somatic glioblastoma arising from MCT-MT in a patient with underlying Li-Fraumeni syndrome. • The rarity of glioblastoma arising from MCT-MT warrants investigation for underlying genetic predisposition. • Glioblastomas arising from MCT-MT appear to exhibit wild type IDH...

Descripción completa

Detalles Bibliográficos
Autores principales: Bussies, Parker L., Chau, Danielle B., Hunt, Jonathan T., Policarpio-Nicolas, Maria Luisa C., Friedman, Cameron, McKenney, Jesse K., Yeaney, Gabrielle A., Peereboom, David M., Beffa, Lindsey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570697/
https://www.ncbi.nlm.nih.gov/pubmed/37840845
http://dx.doi.org/10.1016/j.gore.2023.101279
_version_ 1785119826749947904
author Bussies, Parker L.
Chau, Danielle B.
Hunt, Jonathan T.
Policarpio-Nicolas, Maria Luisa C.
Friedman, Cameron
McKenney, Jesse K.
Yeaney, Gabrielle A.
Peereboom, David M.
Beffa, Lindsey
author_facet Bussies, Parker L.
Chau, Danielle B.
Hunt, Jonathan T.
Policarpio-Nicolas, Maria Luisa C.
Friedman, Cameron
McKenney, Jesse K.
Yeaney, Gabrielle A.
Peereboom, David M.
Beffa, Lindsey
author_sort Bussies, Parker L.
collection PubMed
description • First report of a secondary somatic glioblastoma arising from MCT-MT in a patient with underlying Li-Fraumeni syndrome. • The rarity of glioblastoma arising from MCT-MT warrants investigation for underlying genetic predisposition. • Glioblastomas arising from MCT-MT appear to exhibit wild type IDH gene status. • Advanced-stage glioblastoma arising from MCT-MT exhibits aggressive behavior and requires adjuvant therapy. • Optimal adjuvant therapy regimen for glioblastoma arising from MCT-MT remains unknown.
format Online
Article
Text
id pubmed-10570697
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-105706972023-10-14 Secondary somatic glioblastoma arising from a mature ovarian cystic teratoma in a patient with underlying Li-Fraumeni syndrome Bussies, Parker L. Chau, Danielle B. Hunt, Jonathan T. Policarpio-Nicolas, Maria Luisa C. Friedman, Cameron McKenney, Jesse K. Yeaney, Gabrielle A. Peereboom, David M. Beffa, Lindsey Gynecol Oncol Rep Case Report • First report of a secondary somatic glioblastoma arising from MCT-MT in a patient with underlying Li-Fraumeni syndrome. • The rarity of glioblastoma arising from MCT-MT warrants investigation for underlying genetic predisposition. • Glioblastomas arising from MCT-MT appear to exhibit wild type IDH gene status. • Advanced-stage glioblastoma arising from MCT-MT exhibits aggressive behavior and requires adjuvant therapy. • Optimal adjuvant therapy regimen for glioblastoma arising from MCT-MT remains unknown. Elsevier 2023-09-26 /pmc/articles/PMC10570697/ /pubmed/37840845 http://dx.doi.org/10.1016/j.gore.2023.101279 Text en © 2023 Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Bussies, Parker L.
Chau, Danielle B.
Hunt, Jonathan T.
Policarpio-Nicolas, Maria Luisa C.
Friedman, Cameron
McKenney, Jesse K.
Yeaney, Gabrielle A.
Peereboom, David M.
Beffa, Lindsey
Secondary somatic glioblastoma arising from a mature ovarian cystic teratoma in a patient with underlying Li-Fraumeni syndrome
title Secondary somatic glioblastoma arising from a mature ovarian cystic teratoma in a patient with underlying Li-Fraumeni syndrome
title_full Secondary somatic glioblastoma arising from a mature ovarian cystic teratoma in a patient with underlying Li-Fraumeni syndrome
title_fullStr Secondary somatic glioblastoma arising from a mature ovarian cystic teratoma in a patient with underlying Li-Fraumeni syndrome
title_full_unstemmed Secondary somatic glioblastoma arising from a mature ovarian cystic teratoma in a patient with underlying Li-Fraumeni syndrome
title_short Secondary somatic glioblastoma arising from a mature ovarian cystic teratoma in a patient with underlying Li-Fraumeni syndrome
title_sort secondary somatic glioblastoma arising from a mature ovarian cystic teratoma in a patient with underlying li-fraumeni syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570697/
https://www.ncbi.nlm.nih.gov/pubmed/37840845
http://dx.doi.org/10.1016/j.gore.2023.101279
work_keys_str_mv AT bussiesparkerl secondarysomaticglioblastomaarisingfromamatureovariancysticteratomainapatientwithunderlyinglifraumenisyndrome
AT chaudanielleb secondarysomaticglioblastomaarisingfromamatureovariancysticteratomainapatientwithunderlyinglifraumenisyndrome
AT huntjonathant secondarysomaticglioblastomaarisingfromamatureovariancysticteratomainapatientwithunderlyinglifraumenisyndrome
AT policarpionicolasmarialuisac secondarysomaticglioblastomaarisingfromamatureovariancysticteratomainapatientwithunderlyinglifraumenisyndrome
AT friedmancameron secondarysomaticglioblastomaarisingfromamatureovariancysticteratomainapatientwithunderlyinglifraumenisyndrome
AT mckenneyjessek secondarysomaticglioblastomaarisingfromamatureovariancysticteratomainapatientwithunderlyinglifraumenisyndrome
AT yeaneygabriellea secondarysomaticglioblastomaarisingfromamatureovariancysticteratomainapatientwithunderlyinglifraumenisyndrome
AT peereboomdavidm secondarysomaticglioblastomaarisingfromamatureovariancysticteratomainapatientwithunderlyinglifraumenisyndrome
AT beffalindsey secondarysomaticglioblastomaarisingfromamatureovariancysticteratomainapatientwithunderlyinglifraumenisyndrome