Tetramerization of upstream stimulating factor USF2 requires the elongated bent leucine zipper of the bHLH-LZ domain

Upstream stimulating factors (USFs), including USF1 and USF2, are key components of the transcription machinery that recruit coactivators and histone-modifying enzymes. Using the classic basic helix-loop-helix leucine zipper (bHLH-LZ) domain, USFs bind the E-box DNA and form tetramers that promote D...

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Detalles Bibliográficos
Autores principales: Huang, Cao, Xia, Mingyu, Qiao, Hang, Liu, Zaizhou, Lin, Yuqi, Sun, Hanyin, Yu, Biao, Fang, Pengfei, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570711/
https://www.ncbi.nlm.nih.gov/pubmed/37690682
http://dx.doi.org/10.1016/j.jbc.2023.105240

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