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Cell-permeable peptide nucleic acid antisense oligonucleotide platform targeting human betacoronaviruses

INTRODUCTION: Antisense oligonucleotides (ASOs) with therapeutic potential have recently been reported to target the SARS-CoV-2 genome. Peptide nucleic acids (PNAs)-based ASOs have been regarded as promising drug candidates, but intracellular delivery has been a significant obstacle. Here, we presen...

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Detalles Bibliográficos
Autores principales: Park, Soree, Kim, Seong Ho, Dezhbord, Mehrangiz, Lee, Eun-Hwi, Jeon, Yeasel, Jung, Daram, Gu, Se Hun, Yu, Chiho, Lee, Seung Ho, Kim, Sung Chun, Kim, Kyun-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570754/
https://www.ncbi.nlm.nih.gov/pubmed/37840724
http://dx.doi.org/10.3389/fmicb.2023.1258091