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Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves

The article presents data on the quantification of gallic acid (GA) and the assessment of the antioxidant and anti-inflammatory properties of Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves using various solvents. GA was quantified using high-performance liquid chromatography analysis. T...

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Autores principales: Awang, Mohd Azrie, Benjamin, Mohammad Amil Zulhilmi, Anuar, Adilah, Ismail, Mohd Fakhrulddin, Ramaiya, Shiamala Devi, Mohd Hashim, Siti Nur Aisyah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570934/
https://www.ncbi.nlm.nih.gov/pubmed/37840993
http://dx.doi.org/10.1016/j.dib.2023.109644
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author Awang, Mohd Azrie
Benjamin, Mohammad Amil Zulhilmi
Anuar, Adilah
Ismail, Mohd Fakhrulddin
Ramaiya, Shiamala Devi
Mohd Hashim, Siti Nur Aisyah
author_facet Awang, Mohd Azrie
Benjamin, Mohammad Amil Zulhilmi
Anuar, Adilah
Ismail, Mohd Fakhrulddin
Ramaiya, Shiamala Devi
Mohd Hashim, Siti Nur Aisyah
author_sort Awang, Mohd Azrie
collection PubMed
description The article presents data on the quantification of gallic acid (GA) and the assessment of the antioxidant and anti-inflammatory properties of Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves using various solvents. GA was quantified using high-performance liquid chromatography analysis. Total phenolic content (TPC) was assessed using the Folin-Ciocalteu method. The antioxidant activities were evaluated using xanthine oxidase superoxide (XOD-Superoxide) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) assays, while anti-inflammatory activities were examined through lipoxygenase (LOX) and xanthine oxidase (XOD) inhibition assays. Results showed that the water-extracted sample had the highest GA and TPC among the solvents tested, along with the strongest inhibition activities in the XOD-Superoxide and DPPH assays. Both water and ethanol extracts showed significant inhibitory activities in the LOX assay but were inactive in the XOD assay. These findings suggest that the bioactivity of L. pumila leaf extract is associated with GA and TPC. GA and TPC strongly correlated with antioxidant and anti-inflammatory activities, except for the XOD assay. The dataset highlights the potential dietary benefits of L. pumila leaves as a natural source of antioxidants and anti-inflammatory properties for pharmaceutical and nutraceutical applications.
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spelling pubmed-105709342023-10-14 Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves Awang, Mohd Azrie Benjamin, Mohammad Amil Zulhilmi Anuar, Adilah Ismail, Mohd Fakhrulddin Ramaiya, Shiamala Devi Mohd Hashim, Siti Nur Aisyah Data Brief Data Article The article presents data on the quantification of gallic acid (GA) and the assessment of the antioxidant and anti-inflammatory properties of Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves using various solvents. GA was quantified using high-performance liquid chromatography analysis. Total phenolic content (TPC) was assessed using the Folin-Ciocalteu method. The antioxidant activities were evaluated using xanthine oxidase superoxide (XOD-Superoxide) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) assays, while anti-inflammatory activities were examined through lipoxygenase (LOX) and xanthine oxidase (XOD) inhibition assays. Results showed that the water-extracted sample had the highest GA and TPC among the solvents tested, along with the strongest inhibition activities in the XOD-Superoxide and DPPH assays. Both water and ethanol extracts showed significant inhibitory activities in the LOX assay but were inactive in the XOD assay. These findings suggest that the bioactivity of L. pumila leaf extract is associated with GA and TPC. GA and TPC strongly correlated with antioxidant and anti-inflammatory activities, except for the XOD assay. The dataset highlights the potential dietary benefits of L. pumila leaves as a natural source of antioxidants and anti-inflammatory properties for pharmaceutical and nutraceutical applications. Elsevier 2023-10-05 /pmc/articles/PMC10570934/ /pubmed/37840993 http://dx.doi.org/10.1016/j.dib.2023.109644 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Awang, Mohd Azrie
Benjamin, Mohammad Amil Zulhilmi
Anuar, Adilah
Ismail, Mohd Fakhrulddin
Ramaiya, Shiamala Devi
Mohd Hashim, Siti Nur Aisyah
Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves
title Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves
title_full Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves
title_fullStr Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves
title_full_unstemmed Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves
title_short Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves
title_sort dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from kacip fatimah (labisia pumila benth. & hook. f.) leaves
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570934/
https://www.ncbi.nlm.nih.gov/pubmed/37840993
http://dx.doi.org/10.1016/j.dib.2023.109644
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