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Methods for the identification and preservation of parathyroid glands in thyroid surgery: a narrative review

BACKGROUND AND OBJECTIVE: Accurate intraoperative identification and viability assessment of the parathyroid glands (PGs) has always been a crucial but challenging aspect of thyroid surgery. The traditional method, naked-eye (NE) assessment, is significantly associated with the experience of the sur...

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Autores principales: Pan, Bin, Yuan, Yuquan, Yang, Zeyu, Lu, Dengwei, Long, Tengjiang, Sun, Yiceng, Yin, Supeng, Zhang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570973/
https://www.ncbi.nlm.nih.gov/pubmed/37842534
http://dx.doi.org/10.21037/gs-23-242
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author Pan, Bin
Yuan, Yuquan
Yang, Zeyu
Lu, Dengwei
Long, Tengjiang
Sun, Yiceng
Yin, Supeng
Zhang, Fan
author_facet Pan, Bin
Yuan, Yuquan
Yang, Zeyu
Lu, Dengwei
Long, Tengjiang
Sun, Yiceng
Yin, Supeng
Zhang, Fan
author_sort Pan, Bin
collection PubMed
description BACKGROUND AND OBJECTIVE: Accurate intraoperative identification and viability assessment of the parathyroid glands (PGs) has always been a crucial but challenging aspect of thyroid surgery. The traditional method, naked-eye (NE) assessment, is significantly associated with the experience of the surgeon. Therefore, various methods have been developed to help surgeons protect PGs, with some benefits and limitations. Recently, near-infrared autofluorescence (NIRAF) and indocyanine green fluorescence imaging (ICGFI) have been demonstrated to be promising in the identification and viability assessment of PGs. Herein, we provide an overview of the methods of intraoperative identification and viability assessment of PGs, focusing on the application of NIRAF and ICGFI. METHODS: We performed a systematic literature search of PubMed, Medline, Cochrane Library databases, Web of Science, and EMBASE to identify all relevant studies published up to March 2023. The keywords were ((autofluorescence) OR (indocyanine green)) AND (parathyroid gland). KEY CONTENT AND FINDINGS: In this narrative review, we summarized the benefits and limitations of intraoperative methods for PG identification and viability assessment, focusing on the application of NIRAF and ICGFI. CONCLUSIONS: Intraoperative parathyroid protection methods have developed from traditional subjective identification of PGs to the latest near-infrared (NIR) fluorescence imaging technology. The discovery, development, and application of NIRAF and ICGFI have provided better ways for surgeons to protect PGs intraoperatively.
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spelling pubmed-105709732023-10-14 Methods for the identification and preservation of parathyroid glands in thyroid surgery: a narrative review Pan, Bin Yuan, Yuquan Yang, Zeyu Lu, Dengwei Long, Tengjiang Sun, Yiceng Yin, Supeng Zhang, Fan Gland Surg Review Article BACKGROUND AND OBJECTIVE: Accurate intraoperative identification and viability assessment of the parathyroid glands (PGs) has always been a crucial but challenging aspect of thyroid surgery. The traditional method, naked-eye (NE) assessment, is significantly associated with the experience of the surgeon. Therefore, various methods have been developed to help surgeons protect PGs, with some benefits and limitations. Recently, near-infrared autofluorescence (NIRAF) and indocyanine green fluorescence imaging (ICGFI) have been demonstrated to be promising in the identification and viability assessment of PGs. Herein, we provide an overview of the methods of intraoperative identification and viability assessment of PGs, focusing on the application of NIRAF and ICGFI. METHODS: We performed a systematic literature search of PubMed, Medline, Cochrane Library databases, Web of Science, and EMBASE to identify all relevant studies published up to March 2023. The keywords were ((autofluorescence) OR (indocyanine green)) AND (parathyroid gland). KEY CONTENT AND FINDINGS: In this narrative review, we summarized the benefits and limitations of intraoperative methods for PG identification and viability assessment, focusing on the application of NIRAF and ICGFI. CONCLUSIONS: Intraoperative parathyroid protection methods have developed from traditional subjective identification of PGs to the latest near-infrared (NIR) fluorescence imaging technology. The discovery, development, and application of NIRAF and ICGFI have provided better ways for surgeons to protect PGs intraoperatively. AME Publishing Company 2023-09-14 2023-09-25 /pmc/articles/PMC10570973/ /pubmed/37842534 http://dx.doi.org/10.21037/gs-23-242 Text en 2023 Gland Surgery. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Review Article
Pan, Bin
Yuan, Yuquan
Yang, Zeyu
Lu, Dengwei
Long, Tengjiang
Sun, Yiceng
Yin, Supeng
Zhang, Fan
Methods for the identification and preservation of parathyroid glands in thyroid surgery: a narrative review
title Methods for the identification and preservation of parathyroid glands in thyroid surgery: a narrative review
title_full Methods for the identification and preservation of parathyroid glands in thyroid surgery: a narrative review
title_fullStr Methods for the identification and preservation of parathyroid glands in thyroid surgery: a narrative review
title_full_unstemmed Methods for the identification and preservation of parathyroid glands in thyroid surgery: a narrative review
title_short Methods for the identification and preservation of parathyroid glands in thyroid surgery: a narrative review
title_sort methods for the identification and preservation of parathyroid glands in thyroid surgery: a narrative review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570973/
https://www.ncbi.nlm.nih.gov/pubmed/37842534
http://dx.doi.org/10.21037/gs-23-242
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