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Electrochemical Late-Stage Functionalization
[Image: see text] Late-stage functionalization (LSF) constitutes a powerful strategy for the assembly or diversification of novel molecular entities with improved physicochemical or biological activities. LSF can thus greatly accelerate the development of medicinally relevant compounds, crop protect...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571048/ https://www.ncbi.nlm.nih.gov/pubmed/37751573 http://dx.doi.org/10.1021/acs.chemrev.3c00158 |
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author | Wang, Yulei Dana, Suman Long, Hao Xu, Yang Li, Yanjun Kaplaneris, Nikolaos Ackermann, Lutz |
author_facet | Wang, Yulei Dana, Suman Long, Hao Xu, Yang Li, Yanjun Kaplaneris, Nikolaos Ackermann, Lutz |
author_sort | Wang, Yulei |
collection | PubMed |
description | [Image: see text] Late-stage functionalization (LSF) constitutes a powerful strategy for the assembly or diversification of novel molecular entities with improved physicochemical or biological activities. LSF can thus greatly accelerate the development of medicinally relevant compounds, crop protecting agents, and functional materials. Electrochemical molecular synthesis has emerged as an environmentally friendly platform for the transformation of organic compounds. Over the past decade, electrochemical late-stage functionalization (eLSF) has gained major momentum, which is summarized herein up to February 2023. |
format | Online Article Text |
id | pubmed-10571048 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | American Chemical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-105710482023-10-14 Electrochemical Late-Stage Functionalization Wang, Yulei Dana, Suman Long, Hao Xu, Yang Li, Yanjun Kaplaneris, Nikolaos Ackermann, Lutz Chem Rev [Image: see text] Late-stage functionalization (LSF) constitutes a powerful strategy for the assembly or diversification of novel molecular entities with improved physicochemical or biological activities. LSF can thus greatly accelerate the development of medicinally relevant compounds, crop protecting agents, and functional materials. Electrochemical molecular synthesis has emerged as an environmentally friendly platform for the transformation of organic compounds. Over the past decade, electrochemical late-stage functionalization (eLSF) has gained major momentum, which is summarized herein up to February 2023. American Chemical Society 2023-09-26 /pmc/articles/PMC10571048/ /pubmed/37751573 http://dx.doi.org/10.1021/acs.chemrev.3c00158 Text en © 2023 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Wang, Yulei Dana, Suman Long, Hao Xu, Yang Li, Yanjun Kaplaneris, Nikolaos Ackermann, Lutz Electrochemical Late-Stage Functionalization |
title | Electrochemical
Late-Stage Functionalization |
title_full | Electrochemical
Late-Stage Functionalization |
title_fullStr | Electrochemical
Late-Stage Functionalization |
title_full_unstemmed | Electrochemical
Late-Stage Functionalization |
title_short | Electrochemical
Late-Stage Functionalization |
title_sort | electrochemical
late-stage functionalization |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571048/ https://www.ncbi.nlm.nih.gov/pubmed/37751573 http://dx.doi.org/10.1021/acs.chemrev.3c00158 |
work_keys_str_mv | AT wangyulei electrochemicallatestagefunctionalization AT danasuman electrochemicallatestagefunctionalization AT longhao electrochemicallatestagefunctionalization AT xuyang electrochemicallatestagefunctionalization AT liyanjun electrochemicallatestagefunctionalization AT kaplanerisnikolaos electrochemicallatestagefunctionalization AT ackermannlutz electrochemicallatestagefunctionalization |