The multifaceted role of extracellular vesicles in prostate cancer-a review

Prostate cancer is the second most prominent form of cancer in men and confers the highest mortality after lung cancer. The term “extracellular vesicles” refers to minute endosomal-derived membrane microvesicles and it was demonstrated that extracellular vesicles affect the environment in which tumo...

Descripción completa

Detalles Bibliográficos
Autores principales: Jain, Divya Prakash, Dinakar, Yirivinti Hayagreeva, Kumar, Hitesh, Jain, Rupshee, Jain, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571058/
https://www.ncbi.nlm.nih.gov/pubmed/37842237
http://dx.doi.org/10.20517/cdr.2023.17
_version_ 1785119900504686592
author Jain, Divya Prakash
Dinakar, Yirivinti Hayagreeva
Kumar, Hitesh
Jain, Rupshee
Jain, Vikas
author_facet Jain, Divya Prakash
Dinakar, Yirivinti Hayagreeva
Kumar, Hitesh
Jain, Rupshee
Jain, Vikas
author_sort Jain, Divya Prakash
collection PubMed
description Prostate cancer is the second most prominent form of cancer in men and confers the highest mortality after lung cancer. The term “extracellular vesicles” refers to minute endosomal-derived membrane microvesicles and it was demonstrated that extracellular vesicles affect the environment in which tumors originate. Extracellular vesicles’ involvement is also established in the development of drug resistance, angiogenesis, stemness, and radioresistance in various cancers including prostate cancer. Extracellular vesicles influence the general environment, processes, and growth of prostate cancer and can be a potential area that offers a significant lead in prostate cancer therapy. In this review, we have elaborated on the multifaceted role of extracellular vesicles in various processes involved in the development of prostate cancer, and their multitude of applications in the diagnosis and treatment of prostate cancer through the encapsulation of various bioactives.
format Online
Article
Text
id pubmed-10571058
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher OAE Publishing Inc.
record_format MEDLINE/PubMed
spelling pubmed-105710582023-10-14 The multifaceted role of extracellular vesicles in prostate cancer-a review Jain, Divya Prakash Dinakar, Yirivinti Hayagreeva Kumar, Hitesh Jain, Rupshee Jain, Vikas Cancer Drug Resist Review Prostate cancer is the second most prominent form of cancer in men and confers the highest mortality after lung cancer. The term “extracellular vesicles” refers to minute endosomal-derived membrane microvesicles and it was demonstrated that extracellular vesicles affect the environment in which tumors originate. Extracellular vesicles’ involvement is also established in the development of drug resistance, angiogenesis, stemness, and radioresistance in various cancers including prostate cancer. Extracellular vesicles influence the general environment, processes, and growth of prostate cancer and can be a potential area that offers a significant lead in prostate cancer therapy. In this review, we have elaborated on the multifaceted role of extracellular vesicles in various processes involved in the development of prostate cancer, and their multitude of applications in the diagnosis and treatment of prostate cancer through the encapsulation of various bioactives. OAE Publishing Inc. 2023-07-28 /pmc/articles/PMC10571058/ /pubmed/37842237 http://dx.doi.org/10.20517/cdr.2023.17 Text en © The Author(s) 2023. https://creativecommons.org/licenses/by/4.0/© The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Review
Jain, Divya Prakash
Dinakar, Yirivinti Hayagreeva
Kumar, Hitesh
Jain, Rupshee
Jain, Vikas
The multifaceted role of extracellular vesicles in prostate cancer-a review
title The multifaceted role of extracellular vesicles in prostate cancer-a review
title_full The multifaceted role of extracellular vesicles in prostate cancer-a review
title_fullStr The multifaceted role of extracellular vesicles in prostate cancer-a review
title_full_unstemmed The multifaceted role of extracellular vesicles in prostate cancer-a review
title_short The multifaceted role of extracellular vesicles in prostate cancer-a review
title_sort multifaceted role of extracellular vesicles in prostate cancer-a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571058/
https://www.ncbi.nlm.nih.gov/pubmed/37842237
http://dx.doi.org/10.20517/cdr.2023.17
work_keys_str_mv AT jaindivyaprakash themultifacetedroleofextracellularvesiclesinprostatecancerareview
AT dinakaryirivintihayagreeva themultifacetedroleofextracellularvesiclesinprostatecancerareview
AT kumarhitesh themultifacetedroleofextracellularvesiclesinprostatecancerareview
AT jainrupshee themultifacetedroleofextracellularvesiclesinprostatecancerareview
AT jainvikas themultifacetedroleofextracellularvesiclesinprostatecancerareview
AT jaindivyaprakash multifacetedroleofextracellularvesiclesinprostatecancerareview
AT dinakaryirivintihayagreeva multifacetedroleofextracellularvesiclesinprostatecancerareview
AT kumarhitesh multifacetedroleofextracellularvesiclesinprostatecancerareview
AT jainrupshee multifacetedroleofextracellularvesiclesinprostatecancerareview
AT jainvikas multifacetedroleofextracellularvesiclesinprostatecancerareview

Ejemplares similares