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SG-APSIC1137: 12-hydroxystearic acid upregulates skin antimicrobial peptides in skin models and provides long-lasting protection from bacterial challenge from a handwash formulation

Objectives: We evaluated the role of 12-hydroxystearic acid (12HSA) in upregulating skin antimicrobial peptides (AMPs) in in vitro and ex vivo assays, and 12HSA provides long-lasting germ protection in vivo through a handwash formulation. Methods: In vitro assays were performed by treating skin cell...

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Detalles Bibliográficos
Autores principales: Waskar, Morris, Gu, Xuelan, Mi, Tingyan, Swaminathan, Meenakshi, Vincent, Carol, Ghosh, Rimpa, Doraiswamy, Chandraprabha, Majumdar, Amitabha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571195/
http://dx.doi.org/10.1017/ash.2023.50