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Metformin alleviates adriamycin resistance of osteosarcoma by declining YY1 to inhibit MDR1 transcriptional activity

Chemotherapy resistance hinders the successful treatment of osteosarcoma (OS) to some extent. Previous studies have confirmed that metformin (Met) enhances apoptosis induced by chemotherapeutic drugs, but the underlying mechanism remains unclear. To establish adriamycin (ADM)-resistant MG-63 (MG-63/...

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Detalles Bibliográficos
Autores principales:	Wu, Bowen, Li, Peng, Qiu, Eryue, Chen, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571298/ https://www.ncbi.nlm.nih.gov/pubmed/37828612 http://dx.doi.org/10.1186/s40360-023-00685-8

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