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The prevalence of rheumatic heart disease in Ethiopia: a systematic review and meta-analysis

Globally, more than 33 million people are living with rheumatic heart disease (RHD). A high prevalence of the disease is observed in people with poor socio-economic status, overcrowding, and low access to medical facilities. Even though different studies have been conducted in different settings, th...

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Autores principales: Berhanu, Hiwot, Mekonnen, Yimer, Workicho, Abdulhalik, Hassen, Kalkidan, Negeri, Zenebe, Sudhakar, Morankar, Mitiku, Shimelis, Mossie, Andualem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571304/
https://www.ncbi.nlm.nih.gov/pubmed/37828598
http://dx.doi.org/10.1186/s40794-023-00192-y
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author Berhanu, Hiwot
Mekonnen, Yimer
Workicho, Abdulhalik
Hassen, Kalkidan
Negeri, Zenebe
Sudhakar, Morankar
Mitiku, Shimelis
Mossie, Andualem
author_facet Berhanu, Hiwot
Mekonnen, Yimer
Workicho, Abdulhalik
Hassen, Kalkidan
Negeri, Zenebe
Sudhakar, Morankar
Mitiku, Shimelis
Mossie, Andualem
author_sort Berhanu, Hiwot
collection PubMed
description Globally, more than 33 million people are living with rheumatic heart disease (RHD). A high prevalence of the disease is observed in people with poor socio-economic status, overcrowding, and low access to medical facilities. Even though different studies have been conducted in different settings, there is no reliable data regarding RHD prevalence. Therefore, the aim of this systematic review and meta-analysis was to estimate the pooled prevalence of RHD in Ethiopia. PubMed/Medline, SCOPUS, HINARI, and Google Scholar databases were used to search for peer-reviewed articles. Articles published in English between the years 1992 and 2022 September were considered. The pooled prevalence of RHD was calculated using a random-effect model at a 95% confidence interval, including the weight of each study. Finally, statistical meta-analysis STATA version 16.0 software was used to calculate the pooled prevalence of RHD.A total of twelve cross-sectional studies were included in the meta-analysis. Individual study prevalence ranges from 0.32 to 32.78%. The pooled prevalence of RHD was 3.19% (95% CI: 1.46–5.56%). The prevalence was higher among the population who visited hospitals at 5.42% (95% CI: 1.09–12.7%) compared to schoolchildren at 0.73% (95% CI: 0.30–1.34%) and community-based studies at 3.83% (95% CI: 3.16–4.55%). Addis Ababa had the lowest prevalence of RHD (0.75% (95% CI: 0.38–1.25%), whereas the highest prevalence was observed in the Amhara region (8.95% (95% CI: 7.21–11.06%). A significant variation in the overall estimated prevalence of RHD was not observed between males and females. Trial registration Protocol registration (PROSPERO): CRD42021251553, Date of registration May 28 2021 SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40794-023-00192-y.
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spelling pubmed-105713042023-10-14 The prevalence of rheumatic heart disease in Ethiopia: a systematic review and meta-analysis Berhanu, Hiwot Mekonnen, Yimer Workicho, Abdulhalik Hassen, Kalkidan Negeri, Zenebe Sudhakar, Morankar Mitiku, Shimelis Mossie, Andualem Trop Dis Travel Med Vaccines Review Globally, more than 33 million people are living with rheumatic heart disease (RHD). A high prevalence of the disease is observed in people with poor socio-economic status, overcrowding, and low access to medical facilities. Even though different studies have been conducted in different settings, there is no reliable data regarding RHD prevalence. Therefore, the aim of this systematic review and meta-analysis was to estimate the pooled prevalence of RHD in Ethiopia. PubMed/Medline, SCOPUS, HINARI, and Google Scholar databases were used to search for peer-reviewed articles. Articles published in English between the years 1992 and 2022 September were considered. The pooled prevalence of RHD was calculated using a random-effect model at a 95% confidence interval, including the weight of each study. Finally, statistical meta-analysis STATA version 16.0 software was used to calculate the pooled prevalence of RHD.A total of twelve cross-sectional studies were included in the meta-analysis. Individual study prevalence ranges from 0.32 to 32.78%. The pooled prevalence of RHD was 3.19% (95% CI: 1.46–5.56%). The prevalence was higher among the population who visited hospitals at 5.42% (95% CI: 1.09–12.7%) compared to schoolchildren at 0.73% (95% CI: 0.30–1.34%) and community-based studies at 3.83% (95% CI: 3.16–4.55%). Addis Ababa had the lowest prevalence of RHD (0.75% (95% CI: 0.38–1.25%), whereas the highest prevalence was observed in the Amhara region (8.95% (95% CI: 7.21–11.06%). A significant variation in the overall estimated prevalence of RHD was not observed between males and females. Trial registration Protocol registration (PROSPERO): CRD42021251553, Date of registration May 28 2021 SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40794-023-00192-y. BioMed Central 2023-10-13 /pmc/articles/PMC10571304/ /pubmed/37828598 http://dx.doi.org/10.1186/s40794-023-00192-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Berhanu, Hiwot
Mekonnen, Yimer
Workicho, Abdulhalik
Hassen, Kalkidan
Negeri, Zenebe
Sudhakar, Morankar
Mitiku, Shimelis
Mossie, Andualem
The prevalence of rheumatic heart disease in Ethiopia: a systematic review and meta-analysis
title The prevalence of rheumatic heart disease in Ethiopia: a systematic review and meta-analysis
title_full The prevalence of rheumatic heart disease in Ethiopia: a systematic review and meta-analysis
title_fullStr The prevalence of rheumatic heart disease in Ethiopia: a systematic review and meta-analysis
title_full_unstemmed The prevalence of rheumatic heart disease in Ethiopia: a systematic review and meta-analysis
title_short The prevalence of rheumatic heart disease in Ethiopia: a systematic review and meta-analysis
title_sort prevalence of rheumatic heart disease in ethiopia: a systematic review and meta-analysis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571304/
https://www.ncbi.nlm.nih.gov/pubmed/37828598
http://dx.doi.org/10.1186/s40794-023-00192-y
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