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Affinity hierarchies and amphiphilic proteins underlie the co-assembly of nucleolar and heterochromatin condensates
Nucleoli are surrounded by Pericentromeric Heterochromatin (PCH), reflecting a close spatial association between the two largest biomolecular condensates in eukaryotic nuclei. This nuclear organizational feature is highly conserved and is disrupted in diseased states like senescence, however, the me...
Autores principales: | Rajshekar, Srivarsha, Adame-Arana, Omar, Bajpai, Gaurav, Lin, Kyle, Colmenares, Serafin, Safran, Samuel, Karpen, Gary H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571612/ https://www.ncbi.nlm.nih.gov/pubmed/37841837 http://dx.doi.org/10.21203/rs.3.rs-3385692/v1 |
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