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Transmission of highly virulent CXCR4 tropic HIV-1 through the mucosal route in an individual with a wild-type CCR5 genotype

Nearly all transmitted/founder (T/F) HIV-1 are CCR5 (R5)-tropic. While previous evidence suggested that CXCR4 (X4)-tropic HIV-1 are transmissible, detection was not at the earliest stages of acute infection. Here, we identified an X4-tropic T/F HIV-1 in a participant in acute infection cohort. Corec...

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Detalles Bibliográficos
Autores principales:	Song, Hongshuo, Marichannegowda, Manukumar, Setua, Saini, Bose, Meera, Sanders-Buell, Eric, King, David, Zemil, Michelle, Wieczorek, Lindsay, Diaz-Mendez, Felisa, Chomont, Nicolas, Thomas, Rasmi, Francisco, Leilani, Eller, Leigh Anne, Polonis, Victoria, Tovanabutra, Sodsai, Tagaya, Yutaka, Michael, Nelson, Robb, Merlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571614/ https://www.ncbi.nlm.nih.gov/pubmed/37841838 http://dx.doi.org/10.21203/rs.3.rs-3359209/v1

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