Cargando…

Savolitinib: A Promising Targeting Agent for Cancer

SIMPLE SUMMARY: Savolitinib is a highly specific inhibitor of the MET tyrosine kinase. Both preclinical and clinical studies have shown its potential as a treatment for various cancers, including non-small cell lung cancer (NSCLC) as well as breast, head and neck, colorectal, gastric, pancreatic, an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Tae Seung, Kim, Jun Yeol, Lee, Myeong Hwan, Cho, In Rae, Paik, Woo Hyun, Ryu, Ji Kon, Kim, Yong-Tae, Lee, Sang Hyub
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571651/ https://www.ncbi.nlm.nih.gov/pubmed/37835402 http://dx.doi.org/10.3390/cancers15194708

Ejemplares similares

Efficacy and predictive factors of endoscopic ultrasound-guided ethanol ablation in benign solid pancreatic tumors
por: Choi, Jin Ho, et al.
Publicado: (2023)

Combinatorial Effect of Prophylactic Interventions for Post-ERCP Pancreatitis among Patients with Risk Factors: A Network Meta-Analysis
por: Choi, Jin Ho, et al.
Publicado: (2023)

DAXX/ATRX and MEN1 genes are strong prognostic markers in pancreatic neuroendocrine tumors
por: Park, Joo Kyung, et al.
Publicado: (2017)

High platelet-to-lymphocyte ratio is associated with poor prognosis in patients with unresectable intrahepatic cholangiocarcinoma receiving gemcitabine plus cisplatin
por: Huh, Gunn, et al.
Publicado: (2020)

Comparison between FOLFIRINOX and gemcitabine plus nab-paclitaxel including sequential treatment for metastatic pancreatic cancer: a propensity score matching approach
por: Chun, Jung Won, et al.
Publicado: (2021)

A remnant choledochal cyst after choledochal cyst excision treated with a lumen-apposing metal stent: a case report
por: Kim, Bo Kyung, et al.
Publicado: (2022)

Objective Assessment of Surgical Restaging after Concurrent Chemoradiation for Locally Advanced Pancreatic Cancer
por: Paik, Woo Hyun, et al.
Publicado: (2015)

Duodenal Stricture due to Necrotizing Pancreatitis following Endoscopic Ultrasound-Guided Ethanol Ablation of a Pancreatic Cyst: A Case Report
por: Chun, Jung Won, et al.
Publicado: (2019)

A real-world analysis of nanoliposomal-irinotecan with 5-fluorouracil and folinic acid as third- or later-line therapy in patients with metastatic pancreatic adenocarcinoma
por: Chun, Jung Won, et al.
Publicado: (2022)

Optimal timing of endoscopic retrograde cholangiopancreatography for acute cholangitis associated with distal malignant biliary obstruction
por: Park, Namyoung, et al.
Publicado: (2021)

The effect of nafamostat mesilate infusion after ERCP for post-ERCP pancreatitis
por: Kim, Joo Seong, et al.
Publicado: (2022)

Excision Repair Cross-Complementation Group 6 Gene Polymorphism Is Associated with the Response to FOLFIRINOX Chemotherapy in Asian Patients with Pancreatic Cancer
por: Choi, Young Hoon, et al.
Publicado: (2021)

Role of EUS at high risk for choledocholithiasis without severe cholangitis and visible stone on cross-sectional imaging: A multicenter randomized clinical trial
por: Choi, Young Hoon, et al.
Publicado: (2021)

Gemcitabine plus Nab-paclitaxel as a second-line treatment following FOLFIRINOX failure in advanced pancreatic cancer: a multicenter, single-arm, open-label, phase 2 trial
por: Huh, Gunn, et al.
Publicado: (2021)

Association between glycemic status and the risk of acute pancreatitis: a nationwide population-based study
por: Cho, In Rae, et al.
Publicado: (2023)

Comparison of efficacy between adjuvant chemotherapy and chemoradiation therapy for pancreatic cancer: AJCC stage-based approach
por: You, Min Su, et al.
Publicado: (2020)

Development of novel biliary metal stent with coil-spring structure and its application in vivo swine biliary stricture model
por: Cho, In Rae, et al.
Publicado: (2023)

Risk of cardiovascular disease and mortality in patients with diabetes and acute pancreatitis history: a nationwide cohort study
por: Jang, Dong Kee, et al.
Publicado: (2022)

MicroRNA 141 Expression Is a Potential Prognostic Marker of Biliary Tract Cancers
por: Kim, Jaihwan, et al.
Publicado: (2016)

Human equilibrative nucleoside transporter 1 (hENT1) expression as a predictive biomarker for gemcitabine chemotherapy in biliary tract cancer
por: Kim, Jaihwan, et al.
Publicado: (2018)

Proper adjuvant therapy in patients with borderline resectable and locally advanced pancreatic cancer who had received neoadjuvant FOLFIRINOX
por: Choi, Jin Ho, et al.
Publicado: (2022)

Antiproliferative Activity of Krukovine by Regulating Transmembrane Protein 139 (TMEM139) in Oxaliplatin-Resistant Pancreatic Cancer Cells
por: Lee, Jee-Hyung, et al.
Publicado: (2023)

Mechanisms of Acquired Resistance to Savolitinib, a Selective MET Inhibitor in MET-Amplified Gastric Cancer
por: Frigault, Melanie M., et al.
Publicado: (2020)

Underweight Is Associated with a Higher Risk of Acute Pancreatitis in Type 2 Diabetes: A Nationwide Cohort Study
por: Choi, Young Hoon, et al.
Publicado: (2022)

Innovation of EUS-guided transmural gallbladder drainage using a novel self-expanding metal stent
por: Huh, Gunn, et al.
Publicado: (2020)

Acute Pancreatitis Increases the Risk of Gastrointestinal Cancer in Type 2 Diabetic Patients: A Korean Nationwide Cohort Study
por: Choi, Jin Ho, et al.
Publicado: (2022)

Tumor Marker Kinetics as Prognosticators in Patients with Unresectable Gallbladder Adenocarcinoma Undergoing Palliative Chemotherapy
por: Lee, Jae Woo, et al.
Publicado: (2018)

Additional K-ras mutation analysis and Plectin-1 staining improve the diagnostic accuracy of pancreatic solid mass in EUS-guided fine needle aspiration
por: Park, Joo Kyung, et al.
Publicado: (2017)

Clinical outcomes of endoscopic ultrasound-guided ethanol ablation for pancreatic cystic lesions compared with the natural course: a propensity score matching analysis
por: Choi, Jin Ho, et al.
Publicado: (2018)

Efficacy of Nab-Paclitaxel Plus Gemcitabine and Prognostic Value of Peripheral Neuropathy in Patients with Metastatic Pancreatic Cancer
por: You, Min Su, et al.
Publicado: (2018)

Therapeutic outcomes and prognostic factors in unresectable gallbladder cancer treated with gemcitabine plus cisplatin
por: You, Min su, et al.
Publicado: (2019)

The association between use of statin or aspirin and pancreatic ductal adenocarcinoma: A nested case‐control study in a Korean nationwide cohort
por: Choi, Jin Ho, et al.
Publicado: (2019)

Combination of Docetaxel Plus Savolitinib in Refractory Cancer Patients: A Report on Phase I Trial
por: Kim, Seung Tae, et al.
Publicado: (2019)

Body mass index and weight change during initial period of chemotherapy affect survival outcome in advanced biliary tract cancer patients
por: Kang, Jinwoo, et al.
Publicado: (2018)

Hypertriglyceridaemic waist phenotype and waist circumference triglyceride index are associated with higher incidence of acute pancreatitis: a nationwide population-based retrospective cohort study
por: Chung, Kwang Hyun, et al.
Publicado: (2023)

Genetic susceptibility to post-endoscopic retrograde cholangiopancreatography pancreatitis identified in propensity score-matched analysis
por: Choi, Young Hoon, et al.
Publicado: (2023)

Aspirin for metal stent in malignant distal common bile duct obstruction (AIMS): study protocol for a multicenter randomized controlled trial
por: Choi, Jin Ho, et al.
Publicado: (2020)

Efficacy of Capecitabine Plus Oxaliplatin Combination Chemotherapy for Advanced Pancreatic Cancer after Failure of First-Line Gemcitabine-Based Therapy
por: Chung, Kwang Hyun, et al.
Publicado: (2017)

Impact of balloon inflation on the insertion of endoscopic ultrasound: a prospective, randomized controlled trial
por: Kang, Jinwoo, et al.
Publicado: (2020)

Prognostic Factors for Patients with Borderline Resectable or Locally Advanced Pancreatic Cancer Receiving Neoadjuvant FOLFIRINOX
por: Choi, Young Hoon, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_44sl4f8fjnd6sdr3265eheajla