Cargando…

Up-Front ASCT Overcomes the Survival Benefit Provided by HDAC-Based Induction Regimens in Mantle Cell Lymphoma: Data from a Real-Life and Long-Term Cohort

SIMPLE SUMMARY: This study aimed to assess clinical outcomes, determine survival predictors, and compare responses between different primary therapeutic modalities in a large real-world cohort of patients with mantle cell lymphoma (MCL), with a focus on assessing the impact of intensified immunochem...

Descripción completa

Detalles Bibliográficos
Autores principales:	de Pádua Covas Lage, Luís Alberto, Elias, Marcela do Vale, Reichert, Cadiele Oliana, Culler, Hebert Fabrício, de Freitas, Fábio Alessandro, de Oliveira Costa, Renata, Rocha, Vanderson, da Siqueira, Sheila Aparecida Coelho, Pereira, Juliana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571660/ https://www.ncbi.nlm.nih.gov/pubmed/37835453 http://dx.doi.org/10.3390/cancers15194759

Ejemplares similares

Angioimmunoblastic T-cell lymphoma and correlated neoplasms with T-cell follicular helper phenotype: from molecular mechanisms to therapeutic advances
por: Lage, Luís Alberto de Pádua Covas, et al.
Publicado: (2023)

The role of whole-brain radiotherapy (WBRT) in primary central nervous system lymphoma: is it an alternative to ASCT for consolidation following HD-methotrexate based induction in low-income settings?
por: de Pádua Covas Lage, Luís Alberto, et al.
Publicado: (2022)

Tumor mutation burden involving epigenetic regulatory genes and the RhoA GTPase predicts overall survival in nodal mature T-cell lymphomas
por: de Pádua Covas Lage, Luís Alberto, et al.
Publicado: (2022)

High-dose extended-field radiotherapy plus chemotherapy improved survival in extranodal NK/T-cell lymphoma in a real-life setting: results from the multicenter T-Cell Brazil Project
por: de Pádua Covas Lage, Luís Alberto, et al.
Publicado: (2022)

Acquired hemophagocytic lymphohistiocytosis as initial manifestation of multiple myeloma: A case report and literature review
por: Mendes, Fernanda Rodrigues, et al.
Publicado: (2020)

New genetic prognostic biomarkers in primary central nervous system lymphoma (PCNSL)
por: Gomes Candido Reis, Diego, et al.
Publicado: (2021)

Risk adapted approach: How to treat splenic marginal zone lymphoma in resource-poor settings? - The real-life experience of a Brazilian cancer treatment center
por: de Pádua Covas Lage, Luís Alberto, et al.
Publicado: (2020)

Paraoxonases Activities and Polymorphisms in Elderly and Old-Age Diseases: An Overview
por: Levy, Débora, et al.
Publicado: (2019)

Paraoxonase Role in Human Neurodegenerative Diseases
por: Reichert, Cadiele Oliana, et al.
Publicado: (2020)

Evaluation of Bortezomib-BeEAM (2BeEAM) as Chemotherapy Regimen Prior to ASCT in Patients with Mantle Cell Lymphoma
por: Huwyler, Fabrizio, et al.
Publicado: (2023)

“H” is not for hydroxychloroquine—“H” is for heparin: lack of efficacy of hydroxychloroquine and the role of heparin in COVID-19—preliminary data of a prospective and interventional study from Brazil
por: de Oliveira Costa, Renata, et al.
Publicado: (2022)

Cell Cycle Changes, DNA Ploidy, and PTTG1 Gene Expression in HTLV-1 Patients
por: Levy, Debora, et al.
Publicado: (2020)

Effects of Oxysterols on Immune Cells and Related Diseases
por: de Freitas, Fábio Alessandro, et al.
Publicado: (2022)

Functional and Kinetic Comparison of Alanine Cysteine Serine Transporters ASCT1 and ASCT2
por: Wang, Jiali, et al.
Publicado: (2022)

Ferroptosis Mechanisms Involved in Neurodegenerative Diseases
por: Reichert, Cadiele Oliana, et al.
Publicado: (2020)

ASCT2 is the primary serine transporter in cancer cells
por: Conger, Kelly O., et al.
Publicado: (2023)

Computed tomography findings of diffuse gastrointestinal mantle cell lymphoma
por: Yamauchi, Fernando Ide, et al.
Publicado: (2017)

The Treatment of Multiple Myeloma Patients Not Eligible for Asct
por: Richardson, Paul, et al.
Publicado: (2010)

Interim fluorine-18 fluorodeoxyglucose PET-computed tomography and cell of origin by immunohistochemistry predicts progression-free and overall survival in diffuse large B-cell lymphoma patients in the rituximab era
por: de Oliveira Costa, Renata, et al.
Publicado: (2016)

7-Ketocholesterol Promotes Oxiapoptophagy in Bone Marrow Mesenchymal Stem Cell from Patients with Acute Myeloid Leukemia
por: Paz, Jessica Liliane, et al.
Publicado: (2019)

Proliferative, pro-inflammatory, and angiogenesis regulator gene expression profile defines prognosis in different histopathological subtypes of nodal peripheral T-cell lymphoma
por: de Pádua Covas Lage, Luís Alberto, et al.
Publicado: (2019)

ASCT2 overexpression is associated with poor survival of OSCC patients and ASCT2 knockdown inhibited growth of glutamine‐addicted OSCC cells
por: Luo, Yijun, et al.
Publicado: (2020)

Harnessing Noxa demethylation to overcome Bortezomib resistance in mantle cell lymphoma
por: Leshchenko, Violetta V., et al.
Publicado: (2015)

Extranodal NK-/T-cell lymphoma, nasal type: what advances have been made in the last decade?
por: Costa, Renata de Oliveira, et al.
Publicado: (2023)

Overexpression of OCT-1 gene is a biomarker of adverse prognosis for diffuse large B-cell lymphoma (DLBCL): data from a retrospective cohort of 77 Brazilian patients
por: Gouveia, Gisele R., et al.
Publicado: (2020)

Combined PDGFR and HDAC Inhibition Overcomes PTEN Disruption in Chordoma
por: Lee, Dae-Hee, et al.
Publicado: (2015)

HDAC inhibitors overcome immunotherapy resistance in B-cell lymphoma
por: Wang, Xiaoguang, et al.
Publicado: (2020)

Paraoxonases (PON) 1, 2, and 3 Polymorphisms and PON-1 Activities in Patients with Sickle Cell Disease
por: Reichert, Cadiele Oliana, et al.
Publicado: (2019)

GLUT1 and ASCT2 as Predictors for Prognosis of Hepatocellular Carcinoma
por: Sun, Hong-Wei, et al.
Publicado: (2016)

A difficult case of angioimmunoblastic T-cell lymphoma to diagnose
por: Sachsida-Colombo, Elisabetta, et al.
Publicado: (2016)

Paramount therapy for young and fit patients with mantle cell lymphoma: strategies for front-line therapy
por: Ye, Haige, et al.
Publicado: (2018)

Cytarabine-based induction immunochemotherapy in the front-line treatment of older patients with mantle cell lymphoma
por: Ratnasingam, Sumita, et al.
Publicado: (2019)

Targeting HDAC2-Mediated Immune Regulation to Overcome Therapeutic Resistance in Mutant Colorectal Cancer
por: Conte, Mariarosaria, et al.
Publicado: (2023)

Resistant and disseminated Strongyloides stercoralis infection in a young patient with adult T-cell leukemia/lymphoma
por: Lage, Luís Alberto de Pádua Covas, et al.
Publicado: (2012)

Cotargeting of BTK and MALT1 overcomes resistance to BTK inhibitors in mantle cell lymphoma
por: Jiang, Vivian Changying, et al.
Publicado: (2023)

Overcoming Barriers in Oncolytic Virotherapy with HDAC Inhibitors and Immune Checkpoint Blockade
por: Marchini, Antonio, et al.
Publicado: (2016)

Development of Thiazolidinedione-Based HDAC6 Inhibitors to Overcome Methamphetamine Addiction
por: Sharma, Chiranjeev, et al.
Publicado: (2019)

HDAC6-Selective Inhibitor Overcomes Bortezomib Resistance in Multiple Myeloma
por: Lee, Sang Wu, et al.
Publicado: (2021)

VAD Chemotherapy versus Bortezomib Containing Regimens as Remission Induction For ASCT in Multiple Myeloma: A Single Center Experience
por: Yıkılmaz, Aysun Şentürk, et al.
Publicado: (2020)

Incidental Diagnosis of Mantle Lymphoma Made by Sigmoidoscopy
por: Lage, Jorge, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_dif81cb4vi2kraj2hpe98fo4tf