Overexpression of FRA1 (FOSL1) Leads to Global Transcriptional Perturbations, Reduced Cellular Adhesion and Altered Cell Cycle Progression

FRA1 (FOSL1) is a transcription factor and a member of the activator protein-1 superfamily. FRA1 is expressed in most tissues at low levels, and its expression is robustly induced in response to extracellular signals, leading to downstream cellular processes. However, abnormal FRA1 overexpression ha...

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Detalles Bibliográficos
Autores principales: Al-khayyat, Wuroud, Pirkkanen, Jake, Dougherty, Jessica, Laframboise, Taylor, Dickinson, Noah, Khaper, Neelam, Lees, Simon J., Mendonca, Marc S., Boreham, Douglas R., Tai, Tze Chun, Thome, Christopher, Tharmalingam, Sujeenthar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571788/
https://www.ncbi.nlm.nih.gov/pubmed/37830558
http://dx.doi.org/10.3390/cells12192344

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