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Reproducible Bioinformatics Analysis Workflows for Detecting IGH Gene Fusions in B-Cell Acute Lymphoblastic Leukaemia Patients

SIMPLE SUMMARY: B-cell acute lymphoblastic leukaemia (B-ALL) is a haematological malignancy driven by diverse genomic alterations, the most common being gene fusions, which can be detected via transcriptomic analysis. However, detecting gene fusions involving the Immunoglobulin Heavy Chain (IGH) reg...

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Detalles Bibliográficos
Autores principales: Thomson, Ashlee J., Rehn, Jacqueline A., Heatley, Susan L., Eadie, Laura N., Page, Elyse C., Schutz, Caitlin, McClure, Barbara J., Sutton, Rosemary, Dalla-Pozza, Luciano, Moore, Andrew S., Greenwood, Matthew, Kotecha, Rishi S., Fong, Chun Y., Yong, Agnes S. M., Yeung, David T., Breen, James, White, Deborah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571859/
https://www.ncbi.nlm.nih.gov/pubmed/37835427
http://dx.doi.org/10.3390/cancers15194731