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The Combined Inhibition of Autophagy and Diacylglycerol Acyltransferase-Mediated Lipid Droplet Biogenesis Induces Cancer Cell Death during Acute Amino Acid Starvation
SIMPLE SUMMARY: In this study, the relationship between autophagy and lipid droplets in the response of cancer cells to starvation was investigated. Under conditions of amino acid deprivation, autophagy was triggered and led to lipid droplet accumulation through diacylglycerol acyltransferase (DGAT)...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571868/ https://www.ncbi.nlm.nih.gov/pubmed/37835551 http://dx.doi.org/10.3390/cancers15194857 |