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The Evolving Pathways of the Efficacy of and Resistance to CDK4/6 Inhibitors in Breast Cancer
SIMPLE SUMMARY: Nowadays, the upfront treatment for patients facing a diagnosis of advanced luminal breast cancer (BC) is a combination of endocrine therapy (ET) with an inhibitor of CDK4/6 (CDK4/6i), which effectively targets and prevents cell cycle progression in hormone-dependent BC. However, the...
Autores principales: | Gomes, Inês, Abreu, Catarina, Costa, Luis, Casimiro, Sandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571967/ https://www.ncbi.nlm.nih.gov/pubmed/37835528 http://dx.doi.org/10.3390/cancers15194835 |
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