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UCHL1 Regulates Radiation Lung Injury via Sphingosine Kinase-1

GADD45a is a gene we previously reported as a mediator of responses to acute lung injury. GADD45a−/− mice express decreased Akt and increased Akt ubiquitination due to the reduced expression of UCHL1 (ubiquitin c-terminal hydrolase L1), a deubiquitinating enzyme, while GADD45a−/− mice have increased...

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Detalles Bibliográficos
Autores principales:	Epshtein, Yulia, Mathew, Biji, Chen, Weiguo, Jacobson, Jeffrey R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572187/ https://www.ncbi.nlm.nih.gov/pubmed/37830619 http://dx.doi.org/10.3390/cells12192405

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