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Progress in the Diagnostic and Predictive Evaluation of Crush Syndrome
Crush syndrome (CS), also known as traumatic rhabdomyolysis, is a syndrome with a wide clinical spectrum; it is caused by external compression, which often occurs in earthquakes, wars, and traffic accidents, especially in large-scale disasters. Crush syndrome is the second leading cause of death aft...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572195/ https://www.ncbi.nlm.nih.gov/pubmed/37835777 http://dx.doi.org/10.3390/diagnostics13193034 |
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author | Luo, Yu Liu, Chunli Li, Duo Yang, Bofan Shi, Jie Guo, Xiaoqin Fan, Haojun Lv, Qi |
author_facet | Luo, Yu Liu, Chunli Li, Duo Yang, Bofan Shi, Jie Guo, Xiaoqin Fan, Haojun Lv, Qi |
author_sort | Luo, Yu |
collection | PubMed |
description | Crush syndrome (CS), also known as traumatic rhabdomyolysis, is a syndrome with a wide clinical spectrum; it is caused by external compression, which often occurs in earthquakes, wars, and traffic accidents, especially in large-scale disasters. Crush syndrome is the second leading cause of death after direct trauma in earthquakes. A series of clinical complications caused by crush syndrome, including hyperkalemia, myoglobinuria, and, in particular, acute kidney injury (AKI), is the main cause of death in crush syndrome. The early diagnosis of crush syndrome, the correct evaluation of its severity, and accurate predictions of a poor prognosis can provide personalized suggestions for rescuers to carry out early treatments and reduce mortality. This review summarizes various methods for the diagnostic and predictive evaluation of crush syndrome, including urine dipstick tests for a large number of victims, traditional and emerging biomarkers, imaging-assisted diagnostic methods, and developed evaluation models, with the aim of providing materials for scholars in this research field. |
format | Online Article Text |
id | pubmed-10572195 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-105721952023-10-14 Progress in the Diagnostic and Predictive Evaluation of Crush Syndrome Luo, Yu Liu, Chunli Li, Duo Yang, Bofan Shi, Jie Guo, Xiaoqin Fan, Haojun Lv, Qi Diagnostics (Basel) Review Crush syndrome (CS), also known as traumatic rhabdomyolysis, is a syndrome with a wide clinical spectrum; it is caused by external compression, which often occurs in earthquakes, wars, and traffic accidents, especially in large-scale disasters. Crush syndrome is the second leading cause of death after direct trauma in earthquakes. A series of clinical complications caused by crush syndrome, including hyperkalemia, myoglobinuria, and, in particular, acute kidney injury (AKI), is the main cause of death in crush syndrome. The early diagnosis of crush syndrome, the correct evaluation of its severity, and accurate predictions of a poor prognosis can provide personalized suggestions for rescuers to carry out early treatments and reduce mortality. This review summarizes various methods for the diagnostic and predictive evaluation of crush syndrome, including urine dipstick tests for a large number of victims, traditional and emerging biomarkers, imaging-assisted diagnostic methods, and developed evaluation models, with the aim of providing materials for scholars in this research field. MDPI 2023-09-24 /pmc/articles/PMC10572195/ /pubmed/37835777 http://dx.doi.org/10.3390/diagnostics13193034 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Luo, Yu Liu, Chunli Li, Duo Yang, Bofan Shi, Jie Guo, Xiaoqin Fan, Haojun Lv, Qi Progress in the Diagnostic and Predictive Evaluation of Crush Syndrome |
title | Progress in the Diagnostic and Predictive Evaluation of Crush Syndrome |
title_full | Progress in the Diagnostic and Predictive Evaluation of Crush Syndrome |
title_fullStr | Progress in the Diagnostic and Predictive Evaluation of Crush Syndrome |
title_full_unstemmed | Progress in the Diagnostic and Predictive Evaluation of Crush Syndrome |
title_short | Progress in the Diagnostic and Predictive Evaluation of Crush Syndrome |
title_sort | progress in the diagnostic and predictive evaluation of crush syndrome |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572195/ https://www.ncbi.nlm.nih.gov/pubmed/37835777 http://dx.doi.org/10.3390/diagnostics13193034 |
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