Impact of the Physical Cellular Microenvironment on the Structure and Function of a Model Hepatocyte Cell Line for Drug Toxicity Applications

It is widely recognised that cells respond to their microenvironment, which has implications for cell culture practices. Growth cues provided by 2D cell culture substrates are far removed from native 3D tissue structure in vivo. Geometry is one of many factors that differs between in vitro culture a...

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Detalles Bibliográficos
Autores principales: Allcock, Benjamin, Wei, Wenbin, Goncalves, Kirsty, Hoyle, Henry, Robert, Alisha, Quelch-Cliffe, Rebecca, Hayward, Adam, Cooper, Jim, Przyborski, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572302/
https://www.ncbi.nlm.nih.gov/pubmed/37830622
http://dx.doi.org/10.3390/cells12192408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572302/
https://www.ncbi.nlm.nih.gov/pubmed/37830622
http://dx.doi.org/10.3390/cells12192408

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