Cargando…

Progression after First-Line Cyclin-Dependent Kinase 4/6 Inhibitor Treatment: Analysis of Molecular Mechanisms and Clinical Data

Cyclin-dependent kinase 4/6 inhibitors (CDK4/6iss) are widely used in first-line metastatic breast cancer. For patients with progression under CDK4/6is, there is currently no standard treatment recommended at the category 1 level in international guidelines. The purpose of this article is to review...

Descripción completa

Detalles Bibliográficos
Autores principales:	Villa, Federica, Crippa, Alessandra, Pelizzoni, Davide, Ardizzoia, Alessandra, Scartabellati, Giulia, Corbetta, Cristina, Cipriani, Eleonora, Lavitrano, Marialuisa, Ardizzoia, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572355/ https://www.ncbi.nlm.nih.gov/pubmed/37833875 http://dx.doi.org/10.3390/ijms241914427

Ejemplares similares

AhRR and PPP1R3C: Potential Prognostic Biomarkers for Serous Ovarian Cancer
por: Ardizzoia, Alessandra, et al.
Publicado: (2023)

Specific Expression of a New Bruton Tyrosine Kinase Isoform (p65BTK) in the Glioblastoma Gemistocytic Histotype
por: Sala, Luca, et al.
Publicado: (2019)

Biological and clinical results of a neuroimmunotherapy with interleukin-2 and the pineal hormone melatonin as a first line treatment in advanced non-small cell lung cancer.
por: Lissoni, P., et al.
Publicado: (1992)

Can SARS-CoV-2 Infection Exacerbate Alzheimer’s Disease? An Overview of Shared Risk Factors and Pathogenetic Mechanisms
por: Villa, Chiara, et al.
Publicado: (2022)

Driving the Emission Towards Blue by Controlling the HOMO‐LUMO Energy Gap in BF(2)‐Functionalized 2‐(Imidazo[1,5‐a]pyridin‐3‐yl)phenols
por: Colombo, Gioele, et al.
Publicado: (2021)

Long Non-Coding RNAs and Related Molecular Pathways in the Pathogenesis of Epilepsy
por: Villa, Chiara, et al.
Publicado: (2019)

Exome Sequencing in an ADSHE Family: VUS Identification and Limits
por: Villa, Chiara, et al.
Publicado: (2022)

Role of Cyclin-Dependent Kinase Inhibitors in Endometrial Cancer
por: Giannone, Gaia, et al.
Publicado: (2019)

Metronomic combination of Vinorelbine and 5Fluorouracil is able to inhibit triple-negative breast cancer cells. Results from the proof-of-concept VICTOR-0 study
por: Cerrito, Maria Grazia, et al.
Publicado: (2018)

Molecular and Imaging Biomarkers in Alzheimer’s Disease: A Focus on Recent Insights
por: Villa, Chiara, et al.
Publicado: (2020)

Patient-Derived Induced Pluripotent Stem Cells (iPSCs) and Cerebral Organoids for Drug Screening and Development in Autism Spectrum Disorder: Opportunities and Challenges
por: Villa, Chiara, et al.
Publicado: (2021)

Decrease in cholesterol levels during the immunotherapy of cancer with interleukin-2.
por: Lissoni, P., et al.
Publicado: (1991)

Targeting cyclin-dependent kinases in sarcoma treatment: Current perspectives and future directions
por: Merlini, Alessandra, et al.
Publicado: (2023)

A phase II study of tamoxifen plus melatonin in metastatic solid tumour patients.
por: Lissoni, P., et al.
Publicado: (1996)

Concomitant Presence of p16/Cyclin‐dependent Kinase 4 and Cyclin D/Cyclin‐dependent Kinase 4 omplexes in LNCaP Prostatic Cancer Cell Line
por: Itoh, Noriyuki, et al.
Publicado: (1997)

High-dose-rate brachytherapy as monotherapy for localized prostate cancer using three different doses – 14 years of single-centre experience
por: Soatti, Carlo Pietro, et al.
Publicado: (2020)

Cyclin-dependent kinases
por: Malumbres, Marcos
Publicado: (2014)

Palonosetron in combination with 1-day versus 3-day dexamethasone for prevention of nausea and vomiting following moderately emetogenic chemotherapy: a randomized, multicenter, phase III trial
por: Celio, Luigi, et al.
Publicado: (2010)

Neoadjuvant radiotherapy dose escalation for locally advanced rectal cancers in the new era of radiotherapy: A review of literature
por: Delishaj, Durim, et al.
Publicado: (2021)

Immunotherapy with subcutaneous low-dose interleukin-2 and the pineal indole melatonin as a new effective therapy in advanced cancers of the digestive tract.
por: Lissoni, P., et al.
Publicado: (1993)

A randomised study with subcutaneous low-dose interleukin 2 alone vs interleukin 2 plus the pineal neurohormone melatonin in advanced solid neoplasms other than renal cancer and melanoma.
por: Lissoni, P., et al.
Publicado: (1994)

The Regulation of Cyclins and Cyclin-Dependent Kinases in the Development of Gastric Cancer
por: Javed, Aadil, et al.
Publicado: (2023)

Functional Differentiation of Cyclins and Cyclin-Dependent Kinases in Giardia lamblia
por: Kim, Juri, et al.
Publicado: (2023)

First-line treatment of metastatic castration-resistant prostate cancer: the real-world Italian cohort of the Prostate Cancer Registry
por: Galli, Luca, et al.
Publicado: (2022)

First-Line Treatment with a Cyclin-Dependent Kinase 4/6 Inhibitor Plus an Aromatase Inhibitor for Metastatic Breast Cancer in Alberta
por: Amaro, Carla P., et al.
Publicado: (2021)

BTK, the new kid on the (oncology) block?
por: Grassilli, Emanuela, et al.
Publicado: (2022)

Cyclin-dependent kinases in C. elegans
por: Boxem, Mike
Publicado: (2006)

Cyclin kinase inhibitors and interferons in lupus
por: Theofilopoulos, A
Publicado: (2003)

The Renaissance of Cyclin Dependent Kinase Inhibitors
por: Ettl, Tobias, et al.
Publicado: (2022)

MicroRNA-26a/cyclin-dependent kinase 5 axis controls proliferation, apoptosis and in vivo tumor growth of diffuse large B-cell lymphoma cell lines
por: Farina, Floriana Maria, et al.
Publicado: (2017)

Genetic Status and Expression of the Cyclin‐dependent Kinase Inhibitors in Human Gastric Carcinoma Cell Lines
por: Akama, Yoshihiko, et al.
Publicado: (1996)

Silencing cyclin-dependent kinase inhibitor 3 inhibits the migration of breast cancer cell lines
por: Deng, Miao, et al.
Publicado: (2016)

Co-amplification of Phosphoinositide 3-kinase enhancer A and Cyclin-dependent kinase 4 Triggers Glioblastoma Progression
por: Qi, Qi, et al.
Publicado: (2017)

Cell size and cell cycle progression: the cyclin-dependent kinase link in green algae
por: Jones, Angharad R, et al.
Publicado: (2019)

Phosphorylation of cyclin O, a novel cyclin family protein containing a cyclin-like domain, is involved in the activation of cyclin-dependent kinase 2
por: KIM, DO HYUNG, et al.
Publicado: (2014)

The Cyclin-Dependent Kinase Ortholog pUL97 of Human Cytomegalovirus Interacts with Cyclins
por: Graf, Laura, et al.
Publicado: (2013)

Deciphering the binding behavior of flavonoids to the cyclin dependent kinase 6/cyclin D complex
por: Zhang, Jingxiao, et al.
Publicado: (2018)

Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin B
por: Hégarat, Nadia, et al.
Publicado: (2020)

19q12q13.2 duplication syndrome: neuropsychiatric long-term follow-up of a new case and literature update
por: Nacinovich, Renata, et al.
Publicado: (2017)

Synergism of Cyclin-Dependent Kinase Inhibitors with Camptothecin Derivatives in Small Cell Lung Cancer Cell Lines
por: Hamilton, Gerhard, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_lp1vk9fdc8j901qm7o04pjph8l