EpiPro, a Novel, Synthetic, Activity-Regulated Promoter That Targets Hyperactive Neurons in Epilepsy for Gene Therapy Applications

Epileptogenesis is characterized by intrinsic changes in neuronal firing, resulting in hyperactive neurons and the subsequent generation of seizure activity. These alterations are accompanied by changes in gene transcription networks, first with the activation of early-immediate genes and later with...

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Detalles Bibliográficos
Autores principales: Burke, Cassidy T., Vitko, Iuliia, Straub, Justyna, Nylund, Elsa O., Gawda, Agnieszka, Blair, Kathryn, Sullivan, Kyle A., Ergun, Lara, Ottolini, Matteo, Patel, Manoj K., Perez-Reyes, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572392/
https://www.ncbi.nlm.nih.gov/pubmed/37833914
http://dx.doi.org/10.3390/ijms241914467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572392/
https://www.ncbi.nlm.nih.gov/pubmed/37833914
http://dx.doi.org/10.3390/ijms241914467

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