Cargando…

EpiPro, a Novel, Synthetic, Activity-Regulated Promoter That Targets Hyperactive Neurons in Epilepsy for Gene Therapy Applications

Epileptogenesis is characterized by intrinsic changes in neuronal firing, resulting in hyperactive neurons and the subsequent generation of seizure activity. These alterations are accompanied by changes in gene transcription networks, first with the activation of early-immediate genes and later with...

Descripción completa

Detalles Bibliográficos
Autores principales: Burke, Cassidy T., Vitko, Iuliia, Straub, Justyna, Nylund, Elsa O., Gawda, Agnieszka, Blair, Kathryn, Sullivan, Kyle A., Ergun, Lara, Ottolini, Matteo, Patel, Manoj K., Perez-Reyes, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572392/
https://www.ncbi.nlm.nih.gov/pubmed/37833914
http://dx.doi.org/10.3390/ijms241914467

Ejemplares similares