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Multimodality Imaging in Patients with Hypertrophic Cardiomyopathy and Atrial Fibrillation

Ventricular hypertrophy is associated with diastolic dysfunction, resulting in increased left atrial (LA) pressure, enlargement, fibrosis, and decreased LA function. Hypertrophic cardiomyopathy (HCM) is characterized by myocyte disarray, myocardial fibrosis, and hypertrophy. Notably, a thickened and...

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Autores principales: Chung, Hyemoon, Choi, Eui-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572439/
https://www.ncbi.nlm.nih.gov/pubmed/37835790
http://dx.doi.org/10.3390/diagnostics13193049
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author Chung, Hyemoon
Choi, Eui-Young
author_facet Chung, Hyemoon
Choi, Eui-Young
author_sort Chung, Hyemoon
collection PubMed
description Ventricular hypertrophy is associated with diastolic dysfunction, resulting in increased left atrial (LA) pressure, enlargement, fibrosis, and decreased LA function. Hypertrophic cardiomyopathy (HCM) is characterized by myocyte disarray, myocardial fibrosis, and hypertrophy. Notably, a thickened and noncompliant LV results in the impairment of diastolic function. These conditions promote LA remodeling and enlargement, which contribute to developing and maintaining atrial fibrillation (AF). AF is an atrial arrhythmia that occurs frequently in HCM, and evaluating the morphology and physiology of the atrium and ventricle is important for treatment and prognosis determination in HCM patients with AF. In addition, it provides a clue that can predict the possibility of new AF, even in patients not previously diagnosed with AF. Cardiac magnetic resonance (CMR), which can overcome the limitations of transthoracic echocardiography (TTE), has been widely used traditionally and even enables tissue characterization; moreover, it has emerged as an essential imaging modality for patients with HCM. Here, we review the role of multimodal imaging in patients with HCM and AF.
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spelling pubmed-105724392023-10-14 Multimodality Imaging in Patients with Hypertrophic Cardiomyopathy and Atrial Fibrillation Chung, Hyemoon Choi, Eui-Young Diagnostics (Basel) Review Ventricular hypertrophy is associated with diastolic dysfunction, resulting in increased left atrial (LA) pressure, enlargement, fibrosis, and decreased LA function. Hypertrophic cardiomyopathy (HCM) is characterized by myocyte disarray, myocardial fibrosis, and hypertrophy. Notably, a thickened and noncompliant LV results in the impairment of diastolic function. These conditions promote LA remodeling and enlargement, which contribute to developing and maintaining atrial fibrillation (AF). AF is an atrial arrhythmia that occurs frequently in HCM, and evaluating the morphology and physiology of the atrium and ventricle is important for treatment and prognosis determination in HCM patients with AF. In addition, it provides a clue that can predict the possibility of new AF, even in patients not previously diagnosed with AF. Cardiac magnetic resonance (CMR), which can overcome the limitations of transthoracic echocardiography (TTE), has been widely used traditionally and even enables tissue characterization; moreover, it has emerged as an essential imaging modality for patients with HCM. Here, we review the role of multimodal imaging in patients with HCM and AF. MDPI 2023-09-25 /pmc/articles/PMC10572439/ /pubmed/37835790 http://dx.doi.org/10.3390/diagnostics13193049 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Chung, Hyemoon
Choi, Eui-Young
Multimodality Imaging in Patients with Hypertrophic Cardiomyopathy and Atrial Fibrillation
title Multimodality Imaging in Patients with Hypertrophic Cardiomyopathy and Atrial Fibrillation
title_full Multimodality Imaging in Patients with Hypertrophic Cardiomyopathy and Atrial Fibrillation
title_fullStr Multimodality Imaging in Patients with Hypertrophic Cardiomyopathy and Atrial Fibrillation
title_full_unstemmed Multimodality Imaging in Patients with Hypertrophic Cardiomyopathy and Atrial Fibrillation
title_short Multimodality Imaging in Patients with Hypertrophic Cardiomyopathy and Atrial Fibrillation
title_sort multimodality imaging in patients with hypertrophic cardiomyopathy and atrial fibrillation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572439/
https://www.ncbi.nlm.nih.gov/pubmed/37835790
http://dx.doi.org/10.3390/diagnostics13193049
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