The Tyrosine Phosphatase Activity of PTPN22 Is Involved in T Cell Development via the Regulation of TCR Expression

The protein tyrosine phosphatase PTPN22 inhibits T cell activation by dephosphorylating some essential proteins in the T cell receptor (TCR)-mediated signaling pathway, such as the lymphocyte-specific protein tyrosine kinase (Lck), Src family tyrosine kinases Fyn, and the phosphorylation levels of Z...

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Detalles Bibliográficos
Autores principales: Bai, Bin, Li, Tong, Zhao, Jiahui, Zhao, Yanjiao, Zhang, Xiaonan, Wang, Tao, Zhang, Na, Wang, Xipeng, Ba, Xinlei, Xu, Jialin, Yu, Yang, Wang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572452/
https://www.ncbi.nlm.nih.gov/pubmed/37833951
http://dx.doi.org/10.3390/ijms241914505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572452/
https://www.ncbi.nlm.nih.gov/pubmed/37833951
http://dx.doi.org/10.3390/ijms241914505

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