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Gibbs Energy and Gene Expression Combined as a New Technique for Selecting Drug Targets for Inhibiting Specific Protein–Protein Interactions

One of the most important aspects of successful cancer therapy is the identification of a target protein for inhibition interaction. Conventionally, this consists of screening a panel of genes to assess which is mutated and then developing a small molecule to inhibit the interaction of two proteins...

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Detalles Bibliográficos
Autores principales: Rietman, Edward A., Siegelmann, Hava T., Klement, Giannoula Lakka, Tuszynski, Jack A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572529/
https://www.ncbi.nlm.nih.gov/pubmed/37834096
http://dx.doi.org/10.3390/ijms241914648