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Gibbs Energy and Gene Expression Combined as a New Technique for Selecting Drug Targets for Inhibiting Specific Protein–Protein Interactions
One of the most important aspects of successful cancer therapy is the identification of a target protein for inhibition interaction. Conventionally, this consists of screening a panel of genes to assess which is mutated and then developing a small molecule to inhibit the interaction of two proteins...
Autores principales: | Rietman, Edward A., Siegelmann, Hava T., Klement, Giannoula Lakka, Tuszynski, Jack A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572529/ https://www.ncbi.nlm.nih.gov/pubmed/37834096 http://dx.doi.org/10.3390/ijms241914648 |
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