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The Pro-Oncogenic Protein IF(1) Promotes Proliferation of Anoxic Cancer Cells during Re-Oxygenation

Cancer cells overexpress IF(1), the endogenous protein that inhibits the hydrolytic activity of ATP synthase when mitochondrial membrane potential (Δμ(H)(+)) falls, as in ischemia. Other roles have been ascribed to IF(1), but the associated molecular mechanisms are still under debate. We investigate...

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Detalles Bibliográficos
Autores principales: Righetti, Riccardo, Grillini, Silvia, Del Dotto, Valentina, Costanzini, Anna, Liuzzi, Francesca, Zanna, Claudia, Sgarbi, Gianluca, Solaini, Giancarlo, Baracca, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572598/
https://www.ncbi.nlm.nih.gov/pubmed/37834071
http://dx.doi.org/10.3390/ijms241914624